There are 8 ways to get from Orlando to Florida Keys by plane, bus, shuttle, train, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Key West International Airport, bus
best- Fly from Orlando (MCO) to Key West International Airport (EYW)MCO - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
5h 21m$149–441Bus
cheapest- Take the bus from Orlando to Miami Airport StationFlixBus 2411 / ...
- Take the bus from Miami Airport Station to Big Pine KeyGreyhound US0720s
11h 34m$52–106Bus, shuttle
- Take the bus from Orlando - RedCoach Station, FL to Miami AirportTallahassee-Miami / ...
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
10h 27m$157–262Train, bus
- Take the train from Orlando to Fort Lauderdale Amtrak Station
- Take the train from Fort Lauderdale Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
12h 14m$53–163Drive 355.4 mi
- Drive from Orlando to Florida Keys355.4 mi
7h 16m$65–94Fly Orlando to Miami International Airport, shuttle
- Fly from Orlando (MCO) to Miami International Airport (MIA)MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
7h 55m$219–506Fly Orlando Sanford to Key West International Airport, bus
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)SFB - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
4h 43m$161–499Bus to Tampa, fly to Key West International Airport
- Take the bus from Orlando Bus Station to Tampa Bus Station
- Fly from Tampa (TPA) to Key West International Airport (EYW)TPA - EYW
7h 31m$163–517
Orlando to Florida Keys by bus, shuttle, and foot
Questions & Answers
The cheapest way to get from Orlando to Florida Keys is to bus which costs $50 - $110 and takes 11h 34m.
The fastest way to get from Orlando to Florida Keys is to fly and bus which takes 4h 43m and costs $160 - $500.
No, there is no direct bus from Orlando to Florida Keys. However, there are services departing from Mccoy Rd And Gondola Dr and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Orlando, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 11h 34m.
The distance between Orlando and Florida Keys is 309 miles. The road distance is 357.4 miles.
The best way to get from Orlando to Florida Keys without a car is to bus and shuttle which takes 10h 27m and costs $150 - $270.
It takes approximately 5h 21m to get from Orlando to Florida Keys, including transfers.
Orlando to Florida Keys bus services, operated by Flixbus USA, depart from Orlando station.
Orlando to Florida Keys bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Orlando to Florida Keys is 357 miles. It takes approximately 7h 16m to drive from Orlando to Florida Keys.
There are 799+ hotels available in Florida Keys.
What companies run services between Orlando, FL, USA and Florida Keys, FL, USA?
You can take a bus from Mccoy Rd And Gondola Dr to Florida Keys via Florida Mall Ave And Crystal Clear Ln, Orlando, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 11h 34m.
- Website
- aa.com
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 22m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $45–290
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $30–210
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $110–480
- Website
- southwest.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $30–210
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 17m
- When
- Tuesday and Saturday
- Estimated price
- $55–360
- Website
- spirit.com
Flights from Tampa to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 2h 49m
- When
- Every day
- Estimated price
- $85–380
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Orlando to Fort Lauderdale Amtrak Station
- Ave. Duration
- 4h 47m
- Frequency
- Twice daily
- Estimated price
- $25–120
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-874-7245
- Website
- tri-rail.com
Train from Fort Lauderdale Station to Miami Airport Station
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $4–6
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando - RedCoach Station, FL to Miami Airport
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $24–80
- Website
- https://www.redcoachusa.com
- Web
- $24–80
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $15–25
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $13–25
- Schedules at
- flixbus.com
Bus from Orlando to Miami Airport Station
- Ave. Duration
- 4h 15m
- Frequency
- Every 4 hours
- Estimated price
- $27–60
- Schedules at
- flixbus.com
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