There are 9 ways to get from Orlando to Florida Keys by plane, bus, shuttle, train, car, bus (Greyhound), or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Key West International Airport, bus
best- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
5h 22m$134–411Train, bus
cheapest- Take the train from Orlando to Fort Lauderdale Amtrak Stationtrain
- Take the train from Fort Lauderdale Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
12h 14m$55–96Bus, shuttle
- Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus Tallahassee-Miami / ...
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
10h 27m$157–319Drive 355.4 mi
- Drive from Orlando to Florida Keyscar 355.4 mi
7h 21m$65–94Fly Orlando to Miami International Airport, shuttle
- Fly from Orlando (MCO) to Miami International Airport (MIA)plane MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
7h 55m$214–516Fly Orlando Sanford to Key West International Airport, bus
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
4h 46m$166–539Bus to Tampa, fly to Key West International Airport
- Take the bus from Orlando Bus Station to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
7h 37m$162–466Bus via Pembroke Pines
- Take the bus from Orlando to Sheridan Tri-Rail Stationbus Orlando to Miami Clarion / ...
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
10h 46m$57–105Bus
- Take the bus from Orlando to Miami Airport Stationbus FlixBus 2411 / ...
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
11h 34m$55–96
Orlando to Florida Keys by bus, shuttle, and foot
Questions & Answers
The cheapest way to get from Orlando to Florida Keys is to bus which costs $55 - $100 and takes 11h 34m.
The fastest way to get from Orlando to Florida Keys is to fly and bus which takes 4h 46m and costs $160 - $550.
No, there is no direct bus from Orlando to Florida Keys. However, there are services departing from Mccoy Rd & Gondola Dr and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Orlando, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 11h 34m.
The distance between Orlando and Florida Keys is 309 miles. The road distance is 357.4 miles.
The best way to get from Orlando to Florida Keys without a car is to bus and shuttle which takes 10h 27m and costs $150 - $320.
It takes approximately 5h 22m to get from Orlando to Florida Keys, including transfers.
Orlando to Florida Keys bus services, operated by Flixbus USA, depart from Orlando station.
Orlando to Florida Keys bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Orlando to Florida Keys is 357 miles. It takes approximately 7h 21m to drive from Orlando to Florida Keys.
There are 734+ hotels available in Florida Keys.
What companies run services between Orlando, FL, USA and Florida Keys, FL, USA?
You can take a bus from Orlando to Florida Keys via Sheridan Tri-Rail Station, Sheridan Street Station, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 10h 46m.
- Website
- aa.com
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $50–340
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $30–230
Flights from Tampa to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 7m
- When
- Saturday
- Estimated price
- $55–370
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 16m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $70–470
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 9m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–320
- Website
- southwest.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $30–230
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 20m
- When
- Thursday and Sunday
- Estimated price
- $60–400
- Website
- spirit.com
Flights from Tampa to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 3h 18m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–380
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Orlando to Fort Lauderdale Amtrak Station
- Ave. Duration
- 4h 47m
- Frequency
- Twice daily
- Estimated price
- $26–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-874-7245
- Tri-RailCustomerExperience@sfrta.fl.gov
- Website
- tri-rail.com
Train from Fort Lauderdale Station to Miami Airport Station
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $4–6
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando - RedCoach Station, FL to Miami Airport
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $24–140
- Website
- https://www.redcoachusa.com
- Web
- $24–140
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- https://www.greyhound.com/
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $15–24
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $13–23
- Schedules at
- flixbus.com
Bus from Orlando to Miami Airport Station
- Ave. Duration
- 4h 15m
- Frequency
- Every 4 hours
- Estimated price
- $28–55
- Schedules at
- flixbus.com
- Phone
- (+1) 407 649 4994
- support@miamiorlando.com
- Website
- miamiorlando.com
Bus from Orlando to Sheridan Tri-Rail Station
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $28–40
- Website
- https://miamiorlando.com
- Schedules at
- https://miamiorlando.com/schedule.php
- Book at
- https://miamiorlando.com/search-results.php
- Adult
- $28–40
- Phone
- +1-407-370-3001
- reservations@supertours.com
- Website
- supertours.com
Bus from Orlando to Sheridan Tri-Rail Station
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $45–60
- Schedules at
- supertours.com
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