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How to get fromGainesville to Florida Keysby bus, shuttle, car, plane, bus (Flixbus, Greyhound) or train

Find Transport to Florida Keys

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There are 8 ways to get from Gainesville to Florida Keys by bus, shuttle, car, plane, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, shuttle

    best
    1. Take the bus from Gainesville - Commuter Lot Parking Garage @ Gale Lemerand to Miami Airportbus bus Tallahassee-Miami
    2. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus To the Keys
    12h 42m
    $159–321

  2. Bus, train

    cheapest
    1. Take the bus from Gainesville - Commuter Lot Parking Garage @ Gale Lemerand to West Palm Beach, FLbus bus
    2. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    14h 1m
    $55–191

  3. Drive 459 mi

    1. Drive from Gainesville to Florida Keyscar car 459 mi
    8h 59m
    $84–121

  4. Fly Gainesville Regional Airport to Key West International Airport

    1. Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane plane GNV - EYW
    9h 3m
    $114–490

  5. Bus

    1. Take the bus from Gainesville to Miami Airport Stationbus bus FlixBus 2410 / ...
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    13h 10m
    $74–154

  6. Bus, train via Kissimmee

    1. Take the bus from Gainesville to Orlando RedCoach Stationbus bus
    2. Take the train from Kissimmee Amtrak Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    15h 58m
    $100–322

  7. Bus to Orlando, fly to Key West International Airport

    1. Take the bus from Gainesville to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    7h 38m
    $167–524

  8. Fly Gainesville Regional Airport to Miami International Airport, shuttle

    1. Fly from Gainesville Regional Airport (GNV) to Miami International Airport (MIA)plane plane GNV - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    8h 3m
    $178–486

Gainesville to Florida Keys by bus, shuttle, and foot

Calendar28Weekly Services
Duration12h 42mAverage Duration
Ticket$159Cheapest Price
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Questions & Answers

What companies run services between Gainesville, FL, USA and Florida Keys, FL, USA?

American Airlines and Delta fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Gainesville to Florida Keys via Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 13h 10m.

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