There are 7 ways to get from Cary to Florida Keys by plane, bus (Flixbus, Greyhound), train, bus, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Raleigh-Durham International Airport to Key West International Airport
best- Fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW)RDU - EYW
7h 25m$137–552Train, bus
cheapest- Take the train from Cary to Hollywood Amtrak StationFloridian
- Take the bus from Miami Airport Station to Big Pine KeyGreyhound US0720s
28h 47m$112–324Bus
- Take the bus from Raleigh Bus Station to Orlando Bus Station
- Take the bus from Orlando Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
24h 51m$137–266Drive 936.3 mi
- Drive from Cary to Florida Keys936.3 mi
16h 20m$171–247Fly Raleigh-Durham International Airport to Miami International Airport, shuttle
- Fly from Raleigh-Durham International Airport (RDU) to Miami International Airport (MIA)RDU - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 44m$252–627Fly Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Raleigh-Durham International Airport (RDU) to Fort Lauderdale–Hollywood International Airport (FLL)RDU - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
10h 7m$197–497Train to Charlotte Douglas International Airport, fly to Key West International Airport
- Take the train from Cary to Charlotte Amtrak Station
- Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)CLT - EYW
10h 3m$191–557
Cary to Florida Keys by bus and foot
Questions & Answers
The cheapest way to get from Cary to Florida Keys is to bus which costs $130 - $270 and takes 24h 51m.
The fastest way to get from Cary to Florida Keys is to fly which takes 7h 25m and costs $130 - $550.
No, there is no direct bus from Cary to Florida Keys. However, there are services departing from Cary Depot and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via GoRaleigh Station, Raleigh Bus Station, Orlando Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 24h 51m.
The distance between Cary and Florida Keys is 842 miles. The road distance is 941.8 miles.
The best way to get from Cary to Florida Keys without a car is to bus which takes 24h 51m and costs $130 - $270.
It takes approximately 7h 25m to get from Cary to Florida Keys, including transfers.
Cary to Florida Keys bus services, operated by Flixbus USA, depart from Raleigh Bus Station.
The best way to get from Cary to Florida Keys is to fly which takes 7h 25m and costs $130 - $550. Alternatively, you can bus, which costs $130 - $270 and takes 24h 51m.
Cary to Florida Keys bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Cary to Florida Keys is 942 miles. It takes approximately 16h 20m to drive from Cary to Florida Keys.
What companies run services between Cary, NC, USA and Florida Keys, FL, USA?
Breeze Airways, American Airlines, and Delta fly from Raleigh-Durham International Airport (RDU) to Key West International Airport (EYW) every 2 hours. Alternatively, you can take a bus from Cary Depot to Florida Keys via Union Station - Bus Platform A, GoRaleigh Station, Capital Blvd at Crabtree Blvd, Raleigh Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 24h 51m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $95–490
Flights from Raleigh-Durham International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $90–480
Flights from Raleigh-Durham International Airport to Miami International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $70–370
Flights from Raleigh-Durham International Airport to Miami International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $75–390
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $55–290
Flights from Charlotte Douglas International Airport to Key West International Airport
- Ave. Duration
- 2h 23m
- When
- Every day
- Estimated price
- $75–400
Flights from Charlotte Douglas International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $75–410
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $100–550
Flights from Raleigh-Durham International Airport to Miami International Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $70–370
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $50–280
Flights from Charlotte Douglas International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $85–430
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Miami International Airport via Orlando
- Ave. Duration
- 3h 55m
- When
- Monday to Friday
- Estimated price
- $70–380
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 5m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $50–280
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 3h 52m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $50–290
- Website
- jetblue.com
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 8m
- When
- Every day
- Estimated price
- $50–280
- Website
- spirit.com
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 9m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $45–290
Flights from Charlotte Douglas International Airport to Key West International Airport via Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 50m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $110–450
- Website
- flyfrontier.com
Flights from Raleigh-Durham International Airport to Miami International Airport
- Ave. Duration
- 2h 13m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $70–370
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Key West International Airport
- Ave. Duration
- 2h 30m
- When
- Monday and Friday
- Estimated price
- $200–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Cary to Hollywood Amtrak Station
- Ave. Duration
- 21h 35m
- Frequency
- Once daily
- Estimated price
- $85–280
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $85–240
- Coach Seat short notice purchase
- $120–280
- Business - advance purchase
- $160–700
- Business Class
- $250–650
Train from Cary to Charlotte Amtrak Station
- Ave. Duration
- 2h 58m
- Frequency
- 5 times a day
- Estimated price
- $28–33
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Raleigh Bus Station to Orlando Bus Station
- Ave. Duration
- 11h 10m
- Frequency
- 5 times a week
- Estimated price
- $85–170
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $28–55
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $29–55
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $20–35
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 864+ hotels available in Florida Keys.








