There are 8 ways to get from Manhattan to Depew by plane, train, bus (Flixbus), car, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Laguardia Airport to Buffalo Niagara International Airport
best- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
3h 9m$140–928Bus via Port Authority Bus Terminal
cheapest- Take the bus from Port Authority Bus Terminal to Buffalobus Greyhound US0215 / ...
10h 39m$53–102Train
- Take the train from New York Penn Station to Buffalotrain VIA Rail
9h 13m$63–117Bus (Flixbus)
- Take the bus from New York Midtown to Buffalobus FlixBus 2686 / ...
10h 24m$54–101Drive 351.5 mi
- Drive from Manhattan to Depewcar 351.5 mi
7h 11m$65–93Fly John F. Kennedy International Airport to Buffalo Niagara International Airport
- Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane JFK - BUF
3h 14m$141–839Fly Newark Liberty International Airport to Buffalo Niagara International Airport
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
3h 12m$137–798Fly Laguardia Airport to Rochester, bus
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the bus from Rochester, NY to Buffalo, NYbus
5h 4m$230–683
Manhattan to Depew by train and bus
Questions & Answers
The cheapest way to get from Manhattan to Depew is to drive which costs $60 - $95 and takes 7h 11m.
The fastest way to get from Manhattan to Depew is to fly which takes 3h 9m and costs $140 - $950.
No, there is no direct bus from Manhattan to Depew. However, there are services departing from New York Midtown and arriving at Broadway & Elwood Avenue via Ellicott Street & MTC Static. The journey, including transfers, takes approximately 10h 24m.
The distance between Manhattan and Depew is 305 miles. The road distance is 353.5 miles.
The best way to get from Manhattan to Depew without a car is to train which takes 9h 13m and costs $60 - $120.
It takes approximately 3h 9m to get from Manhattan to Depew, including transfers.
Manhattan to Depew bus services, operated by Flixbus USA, depart from New York Midtown station.
The best way to get from Manhattan to Depew is to fly which takes 3h 9m and costs $140 - $950. Alternatively, you can train, which costs $60 - $120 and takes 9h 13m, you could also bus, which costs $50 - $110 and takes 10h 24m.
Manhattan to Depew bus services, operated by Flixbus USA, arrive at Buffalo station.
Yes, the driving distance between Manhattan to Depew is 354 miles. It takes approximately 7h 11m to drive from Manhattan to Depew.
What companies run services between Manhattan, NY, USA and Depew, NY, USA?
American Airlines and Delta fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, VIA Rail operates a train from New York Penn Station to Buffalo once daily. Tickets cost $60–120 and the journey takes 8h 10m.
- Website
- delta.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $120–900
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $110–800
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $70–490
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $120–900
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h
- When
- Friday and Saturday
- Estimated price
- $140–850
- Website
- united.com
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $100–750
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $130–850
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $110–800
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from New York Penn Station to Buffalo
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.viarail.ca/en
- Economy Adult - same day booking
- $75–120
- Economy Adult - Advanced Booking
- $75–100
- Economy Escape Advanced Booking - Adult
- $60–80
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 25m
- Frequency
- Every 3 hours
- Estimated price
- $50–100
- Schedules at
- flixbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Rochester, NY to Buffalo, NY
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Port Authority Bus Terminal to Buffalo
- Ave. Duration
- 8h 40m
- Frequency
- 4 times a day
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Port Authority Bus Terminal to Buffalo
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $60–95
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
How to get from JFK to New York City
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 204+ hotels available in Depew.