There are 7 ways to get from Manhattan to Depew by plane, train, bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Laguardia Airport
best- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
3h 7m$130–778Bus
cheapest- Take the bus from New York to Buffalobus Adt N816 / ...
9h 58m$64–276Train
- Take the train from New York Penn Station to Buffalotrain VIA Rail
8h 13m$126–290Drive 351.5 mi
- Drive from Manhattan to Depewcar 351.5 mi
7h 10m$65–93Fly from John F. Kennedy International Airport
- Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane JFK - BUF
3h 4m$121–639Fly from Newark Liberty International Airport
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
3h 7m$122–648Bus via New York Midtown (Flixbus)
- Take the bus from New York Midtown to Buffalobus FlixBus N2686 / ...
10h 23m$64–104
Manhattan to Depew by bus
Questions & Answers
The cheapest way to get from Manhattan to Depew is to bus via New York Midtown which costs $60 - $110 and takes 10h 23m.
The fastest way to get from Manhattan to Depew is to fly which takes 3h 4m and costs $120 - $650.
No, there is no direct bus from Manhattan to Depew. However, there are services departing from New York and arriving at Broadway & Elwood Avenue via Ellicott Street & MTC Static. The journey, including transfers, takes approximately 9h 58m.
No, there is no direct train from Manhattan station to Depew. However, there are services departing from New York Penn Station and arriving at Buffalo via . The journey, including transfers, takes approximately 8h 13m.
The distance between Manhattan and Depew is 305 miles. The road distance is 353.5 miles.
The best way to get from Manhattan to Depew without a car is to train which takes 8h 13m and costs $120 - $290.
It takes approximately 3h 7m to get from Manhattan to Depew, including transfers.
Manhattan to Depew bus services, operated by Trailways, depart from New York station.
Manhattan to Depew train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from Manhattan to Depew is to fly which takes 3h 7m and costs $130 - $800. Alternatively, you can train, which costs $120 - $290 and takes 8h 13m, you could also bus, which costs $60 - $280 and takes 9h 58m.
What companies run services between Manhattan, NY, USA and Depew, NY, USA?
American Airlines, Delta, and United Airlines fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, VIA Rail operates a train from New York Penn Station to Buffalo once daily. Tickets cost $110–280 and the journey takes 8h 9m.
- Website
- united.com
Flights from Laguardia Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $150–900
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $85–600
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–700
- Website
- delta.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $110–750
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $90–600
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $90–600
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $110–750
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from New York Penn Station to Buffalo
- Ave. Duration
- 8h 9m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- https://www.viarail.ca/en
- Escape
- $110–260
- Business
- $150–270
- Business Plus
- $160–280
- Economy
- $120–260
- Economy Plus
- $140–270
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from New York to Buffalo
- Ave. Duration
- 8h
- Frequency
- Every 4 hours
- Estimated price
- $60–280
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $60–260
- Flexible
- $110–280
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 25m
- Frequency
- Every 4 hours
- Estimated price
- $60–110
- Schedules at
- flixbus.com
Want to know more about travelling around United States
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More Questions & Answers
Manhattan to Depew bus services, operated by Trailways, arrive at Buffalo station.
Manhattan to Depew train services, operated by VIA Rail, arrive at Buffalo station.
Yes, the driving distance between Manhattan to Depew is 354 miles. It takes approximately 7h 10m to drive from Manhattan to Depew.
Book your Manhattan to Depew train tickets online with Omio.
There are 266+ hotels available in Depew.