There are 5 ways to get from Boston to Depew by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)BOS - BUF
1h 49m$173–941Bus via Syracuse
cheapest- Take the bus from Boston, MA to Syracuse, NYOurBus
- Take the bus from Syracuse, NY to Buffalo, NYOurBus
13h 14m$44–157Bus
- Take the bus from Boston to Syracuse Bus StationFlixBus 2691
- Take the bus from Syracuse Bus Station to BuffaloFlixBus 2686 / ...
12h 18m$79–180Train (Amtrak)
- Take the train from Boston to Buffalo Depew StationLake Shore Limited
12h 42m$135–821Drive 443.1 mi
- Drive from Boston to Depew443.1 mi
7h 49m$81–117
Boston to Depew by bus
Questions & Answers
The cheapest way to get from Boston to Depew is to bus via Syracuse which costs $40 - $160 and takes 13h 14m.
The fastest way to get from Boston to Depew is to fly which takes 1h 49m and costs $170 - $950.
No, there is no direct bus from Boston to Depew. However, there are services departing from Boston and arriving at Broadway & Elwood Avenue via Syracuse Bus Station and Ellicott Street & MTC Static. The journey, including transfers, takes approximately 12h 18m.
The distance between Boston and Depew is 401 miles. The road distance is 445.7 miles.
The best way to get from Boston to Depew without a car is to bus which takes 12h 18m and costs $75 - $180.
It takes approximately 1h 49m to get from Boston to Depew, including transfers.
Boston to Depew bus services, operated by Flixbus USA, depart from Boston station.
The best way to get from Boston to Depew is to fly which takes 1h 49m and costs $170 - $950. Alternatively, you can bus, which costs $75 - $180 and takes 12h 18m, you could also train, which costs $130 - $850 and takes 12h 42m.
Boston to Depew bus services, operated by Flixbus USA, arrive at Syracuse Bus Station.
Yes, the driving distance between Boston to Depew is 446 miles. It takes approximately 7h 49m to drive from Boston to Depew.
What companies run services between Boston, MA, USA and Depew, NY, USA?
American Airlines, JetBlue Airways, and Southwest Airlines fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF) 4 times a day. Alternatively, you can take a bus from Boston to Broadway & Elwood Avenue via Syracuse Bus Station and Ellicott Street & MTC Static in around 12h 18m.
- Website
- aa.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 47m
- When
- Sunday
- Estimated price
- $150–950
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 4h 13m
- When
- Saturday and Sunday
- Estimated price
- $180–1,100
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $200–1,100
- Website
- jetblue.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $150–950
- Website
- southwest.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 20m
- When
- Wednesday and Thursday
- Estimated price
- $190–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 39m
- Frequency
- Once daily
- Estimated price
- $130–850
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 35m
- Frequency
- 6 times a week
- Estimated price
- $50–130
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $27–45
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $50–140
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $27–45
- Website
- https://www.greyhound.com/
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- $25–40
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Boston, MA to Syracuse, NY
- Ave. Duration
- 6h 25m
- Frequency
- Twice a week
- Estimated price
- $20–90
- Website
- https://www.ourbus.com
Bus from Syracuse, NY to Buffalo, NY
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a week
- Estimated price
- $20–65
- Website
- https://www.ourbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 223+ hotels available in Depew.