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How to get fromBoston to Depewby plane, bus (Greyhound), train (Amtrak), car or bus (Flixbus)

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There are 5 ways to get from Boston to Depew by plane, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    1h 41m
    $152–855

  2. Bus via Ithaca

    cheapest
    1. Take the bus from Boston to Ithacabus bus FlixBus 2691
    2. Take the bus from Ithaca to Buffalobus bus FlixBus N2687 / ...
    14h 23m
    $80–187

  3. Bus (Greyhound)

    1. Take the bus from Boston to Buffalobus bus Greyhound US0171
    12h 4m
    $84–156

  4. Train (Amtrak)

    1. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    12h 42m
    $140–303

  5. Drive 443.2 mi

    1. Drive from Boston to Depewcar car 443.2 mi
    7h 51m
    $81–117

Boston to Depew by bus (Greyhound)

Calendar7Weekly Buses
Duration12h 4mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

What companies run services between Boston, MA, USA and Depew, NY, USA?

American Airlines, JetBlue Airways, and three other airlines fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, Greyhound USA operates a bus from Boston to Buffalo once daily. Tickets cost $80–160 and the journey takes 10h 5m.

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