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How to get fromBoston to Depewby plane, bus (Greyhound, Flixbus), train (Amtrak), car or bus

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There are 5 ways to get from Boston to Depew by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    1h 49m
    $167–937

  2. Bus via Syracuse

    cheapest
    1. Take the bus from Boston, MA to Syracuse, NYbus bus OurBus
    2. Take the bus from Syracuse, NY to Buffalo, NYbus bus OurBus
    13h 14m
    $44–157

  3. Bus

    1. Take the bus from Boston to Syracuse Bus Stationbus bus Greyhound US0270
    2. Take the bus from Syracuse Bus Station to Buffalobus bus FlixBus 2686 / ...
    12h 19m
    $73–158

  4. Train (Amtrak)

    1. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    12h 42m
    $127–451

  5. Drive 443.2 mi

    1. Drive from Boston to Depewcar car 443.2 mi
    7h 51m
    $81–117

Boston to Depew by bus

Calendar12Weekly Buses
Duration12h 19mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

What companies run services between Boston, MA, USA and Depew, NY, USA?

American Airlines, JetBlue Airways, and three other airlines fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF) every 2 hours. Alternatively, you can take a bus from Boston to Broadway & Elwood Avenue via Syracuse Bus Station and Ellicott Street & MTC Static in around 12h 19m.

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