There are 6 ways to get from Chicago to Depew by plane, train (Amtrak), bus, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Chicago Midway International Airport
best- Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane MDW - BUF
3h 5m$220–1,226Bus
cheapest- Take the bus from Chicago to Clevelandbus Chicago
- Take the bus from Cleveland, OH to Buffalo, NYbus Cinncinati,OH-Buffalo
13h 4m$54–141Train (Amtrak)
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain Lake Shore Limited
11h 26m$146–317Drive 535.6 mi
- Drive from Chicago to Depewcar 535.6 mi
9h 9m$98–142Fly from Chicago O'Hare International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane ORD - BUF
3h 35m$160–876Bus via Brook Park (Greyhound)
- Take the bus from Chicago Bus Station to Cleveland Bus Stationbus Greyhound US0164
- Take the bus from Cleveland Bus Station to Buffalobus Greyhound US0171 / ...
13h 39m$89–174
Chicago to Depew by train and bus (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Depew is to bus which costs $50 - $150 and takes 13h 4m.
The fastest way to get from Chicago to Depew is to fly which takes 3h 5m and costs $220 - $1,300.
No, there is no direct bus from Chicago to Depew. However, there are services departing from Chicago and arriving at Broadway & Elwood Avenue via Cleveland, OH and Ellicott Street & MTC Static. The journey, including transfers, takes approximately 13h 4m.
The distance between Chicago and Depew is 484 miles. The road distance is 538.7 miles.
The best way to get from Chicago to Depew without a car is to train which takes 11h 26m and costs $140 - $320.
It takes approximately 3h 5m to get from Chicago to Depew, including transfers.
Chicago to Depew bus services, operated by Barons Bus, depart from Chicago station.
The best way to get from Chicago to Depew is to fly which takes 3h 5m and costs $220 - $1,300. Alternatively, you can train, which costs $140 - $320 and takes 11h 26m, you could also bus, which costs $50 - $150 and takes 13h 4m.
Chicago to Depew bus services, operated by Barons Bus, arrive at Cleveland station.
Depew is 1h ahead of Chicago. It is currently 6:53 PM in Chicago and 7:53 PM in Depew.
What companies run services between Chicago, IL, USA and Depew, NY, USA?
Southwest Airlines flies from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF) 3 times a day. Alternatively, Amtrak operates a train from Chicago Union Station to Buffalo Depew Station twice daily. Tickets cost $140–320 and the journey takes 10h 23m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $200–1,200
- Website
- united.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $140–850
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $140–850
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $140–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $140–320
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Chicago to Cleveland
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Cleveland Bus Station
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Buffalo
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Chicago to Depew is 539 miles. It takes approximately 9h 9m to drive from Chicago to Depew.
There are 474+ hotels available in Depew.