There are 7 ways to get from Philadelphia to Depew by plane, train (Amtrak), bus (Flixbus, Greyhound), car, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Philadelphia International Airport
best- Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane PHL - BUF
3h 1m$140–924Drive 335.2 mi
cheapest- Drive from Philadelphia to Depewcar 335.2 mi
7h 2m$62–89Train (Amtrak)
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain Keystone Service / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Stationtrain Empire Service / ...
11h 28m$143–868Bus
- Take the bus from Philadelphia Bus Station to Newark Penn Stationbus FlixBus 2601 / ...
- Take the bus from Newark Penn Station to Buffalobus FlixBus 2686 / ...
12h 44m$63–157Train to Baltimore-Washington International Airport, fly
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane BWI - BUF
3h 53m$136–1,329Train to Newark Liberty International Airport, fly
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
3h 47m$120–669Bus via Scranton (Greyhound)
- Take the bus from Philadelphia Bus Station to Scranton Bus Stationbus Greyhound US0340s
- Take the bus from Scranton Bus Station to Buffalobus Greyhound US0215
14h 59m$71–143
Philadelphia to Depew by train and bus (Amtrak)
Questions & Answers
The cheapest way to get from Philadelphia to Depew is to drive which costs $60 - $90 and takes 7h 2m.
The fastest way to get from Philadelphia to Depew is to fly which takes 3h 1m and costs $140 - $950.
No, there is no direct bus from Philadelphia station to Depew. However, there are services departing from Philadelphia Bus Station and arriving at Broadway & Elwood Avenue via Newark Penn Station and Ellicott Street & MTC Static. The journey, including transfers, takes approximately 12h 44m.
The distance between Philadelphia and Depew is 293 miles. The road distance is 337.1 miles.
The best way to get from Philadelphia to Depew without a car is to train which takes 11h 28m and costs $140 - $900.
It takes approximately 3h 1m to get from Philadelphia to Depew, including transfers.
Philadelphia to Depew bus services, operated by Flixbus USA, depart from Philadelphia Bus Station.
The best way to get from Philadelphia to Depew is to fly which takes 3h 1m and costs $140 - $950. Alternatively, you can train, which costs $140 - $900 and takes 11h 28m, you could also bus, which costs $60 - $160 and takes 12h 44m.
Philadelphia to Depew bus services, operated by Flixbus USA, arrive at Newark Penn Station.
Yes, the driving distance between Philadelphia to Depew is 337 miles. It takes approximately 7h 2m to drive from Philadelphia to Depew.
What companies run services between Philadelphia, PA, USA and Depew, NY, USA?
American Airlines and United Airlines fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a train from 30th Street Station to Broadway & Canton Street via Ny Moynihan Train Hall At Penn Station, Buffalo Depew Station, and Broadway & Dick Road in around 11h 28m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $95–700
- Website
- united.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $150–1,000
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $80–600
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 52m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–700
- Website
- aa.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $120–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $25–55
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Station
- Ave. Duration
- 8h 1m
- Frequency
- 4 times a day
- Estimated price
- $120–270
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- $22–50
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $20–460
- First Class
- $130–600
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $24–460
- First Class
- $140–650
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Philadelphia Bus Station to Newark Penn Station
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- $10–18
- Schedules at
- flixbus.com
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 7h 55m
- Frequency
- Every 4 hours
- Estimated price
- $50–90
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Philadelphia Bus Station to Newark Penn Station
- Ave. Duration
- 1h 55m
- Frequency
- Every 3 hours
- Estimated price
- $13–26
- Website
- https://www.greyhound.com/
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Philadelphia Bus Station to Scranton Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $23–50
- Website
- https://www.greyhound.com/
Bus from Scranton Bus Station to Buffalo
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
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