There are 10 ways to get from Philadelphia to Depew by plane, train (Amtrak), bus (Flixbus, Greyhound), car, train, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Philadelphia International Airport to Buffalo Niagara International Airport
best- Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane PHL - BUF
3h 7m$165–989Drive 335.2 mi
cheapest- Drive from Philadelphia to Depewcar 335.2 mi
7h 1m$62–89Train
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain Northeast Regional
- Take the train from New York Penn Station to Buffalotrain VIA Rail
11h 39m$75–718Bus
- Take the bus from Philadelphia to Newark Penn Stationbus FlixBus 2601 / ...
- Take the bus from Newark Penn Station to Buffalobus FlixBus 2686 / ...
12h 34m$69–153Train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane BWI - BUF
3h 58m$157–1,529Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
3h 52m$137–1,040Train to Laguardia Airport, fly to Buffalo Niagara International Airport
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
5h 16m$176–1,583Fly Philadelphia International Airport to Rochester, bus
- Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane PHL - ROC
- Take the bus from Rochester, NY to Buffalo, NYbus
5h 2m$184–470Train via Galleria Driveway & Green Parking Entrance (Amtrak)
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain Northeast Regional
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Stationtrain Maple Leaf / ...
12h 30m$77–750Bus via Scranton
- Take the bus from Philadelphia, PA to Scranton, PAbus 202 / ...
- Take the bus from Scranton Bus Station to Buffalobus Greyhound US0215
12h 44m$102–166
Philadelphia to Depew by train and bus
Questions & Answers
The cheapest way to get from Philadelphia to Depew is to drive which costs $60 - $90 and takes 7h 1m.
The fastest way to get from Philadelphia to Depew is to fly which takes 3h 7m and costs $160 - $1,000.
No, there is no direct bus from Philadelphia to Depew. However, there are services departing from Philadelphia and arriving at Broadway & Elwood Avenue via Newark Penn Station and Ellicott Street & MTC Static. The journey, including transfers, takes approximately 12h 34m.
The distance between Philadelphia and Depew is 293 miles. The road distance is 337.1 miles.
The best way to get from Philadelphia to Depew without a car is to train which takes 11h 39m and costs $70 - $750.
It takes approximately 3h 7m to get from Philadelphia to Depew, including transfers.
Philadelphia to Depew bus services, operated by Flixbus USA, depart from Philadelphia station.
The best way to get from Philadelphia to Depew is to fly which takes 3h 7m and costs $160 - $1,000. Alternatively, you can train, which costs $70 - $750 and takes 11h 39m, you could also bus, which costs $65 - $160 and takes 12h 34m.
Philadelphia to Depew bus services, operated by Flixbus USA, arrive at Newark Penn Station.
Yes, the driving distance between Philadelphia to Depew is 337 miles. It takes approximately 7h 1m to drive from Philadelphia to Depew.
What companies run services between Philadelphia, PA, USA and Depew, NY, USA?
American Airlines and United Airlines fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF) 5 times a day. Alternatively, you can take a train from 30th Street Station to Broadway & Canton Street via Ny Moynihan Train Hall At Penn Station, New York Penn Station, Buffalo, and Broadway & Dick Road in around 11h 39m.
- Website
- aa.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $140–1,000
Flights from Philadelphia International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $170–1,100
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $140–950
Flights from Philadelphia International Airport to Rochester
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $75–550
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $130–900
- Website
- united.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $170–1,100
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $110–800
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $140–900
Flights from Philadelphia International Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $90–600
- Website
- delta.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $140–950
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 26m
- Frequency
- Hourly
- Estimated price
- $12–230
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $12–230
- Business Class
- $60–270
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $14–240
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $14–240
- Business Class
- $60–280
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 57 min
- Frequency
- Every 2 hours
- Estimated price
- $10–220
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $10–220
- Business Class
- $55–260
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $18–270
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 27m
- Frequency
- Twice daily
- Estimated price
- $10–210
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 1h 2m
- Frequency
- Twice a week
- Estimated price
- $10–65
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $18–29
- Coach Seat short notice purchase
- $10–65
- Business - advance purchase
- $13–95
- Business Class
- $23–180
Train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Station
- Ave. Duration
- 8h 4m
- Frequency
- 4 times a day
- Estimated price
- $60–150
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 2 hours
- Estimated price
- $20–600
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $20–460
- First Class
- $130–600
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 24m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $24–460
- First Class
- $140–650
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from New York Penn Station to Buffalo
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.viarail.ca/en
- Economy Adult - same day booking
- $75–120
- Economy Adult - Advanced Booking
- $75–100
- Economy Escape Advanced Booking - Adult
- $60–80
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Philadelphia to Newark Penn Station
- Ave. Duration
- 1h 50m
- Frequency
- Every 3 hours
- Estimated price
- $18–40
- Schedules at
- flixbus.com
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 7h 45m
- Frequency
- 5 times a day
- Estimated price
- $50–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Philadelphia to Newark Penn Station
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- $17–45
- Website
- https://www.greyhound.com/
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from Scranton Bus Station to Buffalo
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Rochester, NY to Buffalo, NY
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
- Phone
- +1 800-233-8604
- Website
- martzbus.com
Bus from Philadelphia, PA to Scranton, PA
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Website
- https://martzbus.com
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