There are 7 ways to get from Mainz to Nyon by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Mannheim
best- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Renens VDtrain
6h 48mCHF 82–227Bus
cheapest- Take the bus from Frankfurt Airport to Genevabus FlixBus N122
11h 32mCHF 46–88Drive 546 km
- Drive from Mainz to Nyoncar 546 km
5h 3mCHF 92–133Fly to Geneva International Airport
- Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane FRA - GVA
4h 22mCHF 111–280Train
- Take the train from Mainz Hbf to Basel SBBtrain Nightjet
- Take the train from Basel SBB to Renens VDtrain Ic51
8h 5mCHF 87–215Fly to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)plane FRA - BSL
- Take the train from Basel SBB to Renens VDtrain
6h 8mCHF 164–418Fly to Zurich Airport, train
- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane FRA - ZRH
- Take the train from Zürich Flughafen to Nyontrain
6h 16mCHF 164–328
Mainz to Nyon by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Nyon is to bus which costs SFr 45 - SFr 90 and takes 11h 32m.
The fastest way to get from Mainz to Nyon is to fly which takes 4h 22m and costs SFr 110 - SFr 280.
No, there is no direct bus from Mainz to Nyon. However, there are services departing from Mainz, Hauptbahnhof and arriving at Geneva via Frankfurt Airport. The journey, including transfers, takes approximately 11h 32m.
No, there is no direct train from Mainz to Nyon. However, there are services departing from Mainz, Hauptbahnhof and arriving at Nyon via Mannheim, Hauptbahnhof, Basel SBB and Renens VD. The journey, including transfers, takes approximately 6h 48m.
The distance between Mainz and Nyon is 530 km. The road distance is 546 km.
The best way to get from Mainz to Nyon without a car is to train via Mannheim which takes 6h 48m and costs SFr 80 - SFr 230.
It takes approximately 6h 48m to get from Mainz to Nyon, including transfers.
Mainz to Nyon bus services, operated by FlixBus, depart from Frankfurt Airport station.
Mainz to Nyon train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Nyon is to train via Mannheim which takes 6h 48m and costs SFr 80 - SFr 230. Alternatively, you can bus, which costs SFr 45 - SFr 90 and takes 11h 32m, you could also fly, which costs SFr 110 - SFr 280 and takes 4h 22m.
What companies run services between Mainz, Germany and Nyon, Switzerland?
You can take a train from Mainz, Hauptbahnhof to Nyon via Mannheim, Hauptbahnhof, Basel SBB, and Renens VD in around 6h 48m. Alternatively, FlixBus operates a bus from Frankfurt Airport to Geneva 5 times a week. Tickets cost CHF 45–70 and the journey takes 8h 55m. BlaBlaCar Bus also services this route 4 times a week.
- Website
- lufthansa.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- CHF 85–400
Flights from Frankfurt to Geneva International Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- CHF 85–450
Flights from Frankfurt to Basel
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- CHF 75–390
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- CHF 75–370
- Website
- swiss.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- CHF 85–400
Flights from Frankfurt to Geneva International Airport via Zurich Airport
- Ave. Duration
- 3h 7m
- When
- Monday to Saturday
- Estimated price
- CHF 85–320
Flights from Frankfurt to Basel
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- CHF 75–180
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- CHF 75–370
- Website
- airdolomiti.it
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Sunday
- Estimated price
- CHF 120–400
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 130–390
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 120–370
- Website
- condor.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- CHF 85–200
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- CHF 12–24
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- CHF 40–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz Hbf to Basel SBB
- Ave. Duration
- 4h 38m
- Frequency
- Once a week
- Estimated price
- CHF 60–130
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- CHF 10–50
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- CHF 13–19
- Schedules at
- Süwex
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Twice daily
- Estimated price
- CHF 7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- CHF 26–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz Hbf to Basel SBB
- Ave. Duration
- 4h 38m
- Frequency
- Twice daily
- Estimated price
- CHF 35–75
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- CHF 45–75
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- CHF 45–75
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- CHF 45–75
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich Flughafen to Nyon
- Ave. Duration
- 3h 13m
- Frequency
- Hourly
- Estimated price
- CHF 70–110
- Website
- Swiss Federal Railways (SBB CFF FFS)
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Frankfurt Airport to Geneva
- Ave. Duration
- 8h 55m
- Frequency
- 5 times a week
- Estimated price
- CHF 45–70
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Frankfurt Airport to Geneva
- Ave. Duration
- 10h 20m
- Frequency
- 4 times a week
- Estimated price
- CHF 35–60
- Website
- BlaBlaCar Bus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Mainz to Nyon bus services, operated by FlixBus, arrive at Geneva station.
Mainz to Nyon train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Nyon is 546 km. It takes approximately 5h 3m to drive from Mainz to Nyon.
Book your Mainz to Nyon train tickets online with Omio.
Book your Mainz to Nyon bus tickets online with Omio.
There are 1512+ hotels available in Nyon.





























