There are 7 ways to get from Mainz to Nyon by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Mannheim
best- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Renens VDtrain
6h 48mCHF 97–419Bus
cheapest- Take the bus from Frankfurt Airport to Genevabus FlixBus N122
11h 20mCHF 51–113Drive 546 km
- Drive from Mainz to Nyoncar 546 km
5h 3mCHF 90–130Fly to Geneva International Airport
- Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane FRA - GVA
4h 23mCHF 134–280Train
- Take the train from Mainz Hbf to Basel SBBtrain Nightjet
- Take the train from Basel SBB to Renens VDtrain Ic51
8h 5mCHF 102–448Fly to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)plane FRA - BSL
- Take the train from Basel SBB to Renens VDtrain
6h 10mCHF 182–522Fly to Zurich Airport, train
- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane FRA - ZRH
- Take the train from Zürich Flughafen to Nyontrain
6h 17mCHF 180–482
Mainz to Nyon by train
Questions & Answers
The cheapest way to get from Mainz to Nyon is to bus which costs SFr 50 - SFr 120 and takes 11h 20m.
The fastest way to get from Mainz to Nyon is to fly which takes 4h 23m and costs SFr 130 - SFr 280.
No, there is no direct bus from Mainz to Nyon. However, there are services departing from Ginsheim-Gustavsburg-Gustavsburg Am Alten Fährhaus and arriving at Geneva via Frankfurt Airport. The journey, including transfers, takes approximately 11h 20m.
No, there is no direct train from Mainz to Nyon. However, there are services departing from Mainz, Hauptbahnhof and arriving at Nyon via Mannheim, Hauptbahnhof, Basel SBB and Renens VD. The journey, including transfers, takes approximately 6h 48m.
The distance between Mainz and Nyon is 530 km. The road distance is 546 km.
The best way to get from Mainz to Nyon without a car is to train via Mannheim which takes 6h 48m and costs SFr 95 - SFr 420.
It takes approximately 6h 48m to get from Mainz to Nyon, including transfers.
Mainz to Nyon bus services, operated by FlixBus, depart from Frankfurt Airport station.
Mainz to Nyon train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Nyon is to train via Mannheim which takes 6h 48m and costs SFr 95 - SFr 420. Alternatively, you can bus, which costs SFr 50 - SFr 120 and takes 11h 20m, you could also fly, which costs SFr 130 - SFr 280 and takes 4h 23m.
What companies run services between Mainz, Germany and Nyon, Switzerland?
You can take a train from Mainz, Hauptbahnhof to Nyon via Mannheim, Hauptbahnhof, Basel SBB, and Renens VD in around 6h 48m. Alternatively, FlixBus operates a bus from Frankfurt Airport to Geneva once daily. Tickets cost CHF 40–75 and the journey takes 8h 55m. BlaBlaCar Bus also services this route once daily.
- Website
- lufthansa.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 95–550
Flights from Frankfurt to Geneva International Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- CHF 150–700
Flights from Frankfurt to Basel
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- CHF 90–550
Flights from Frankfurt to Basel via Munich
- Ave. Duration
- 2h 40m
- When
- Monday, Wednesday, Thursday, Saturday, and Friday
- Estimated price
- CHF 45–390
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- CHF 65–500
- Website
- swiss.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 95–550
Flights from Frankfurt to Geneva International Airport via Zurich Airport
- Ave. Duration
- 2h 56m
- When
- Every day
- Estimated price
- CHF 95–600
Flights from Frankfurt to Basel
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- CHF 90–370
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- CHF 65–500
- Website
- airdolomiti.it
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- CHF 130–550
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Monday, Saturday, and Sunday
- Estimated price
- CHF 130–550
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Sunday
- Estimated price
- CHF 120–500
- Website
- condor.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- CHF 75–180
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- CHF 12–45
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- CHF 40–160
- Website
- https://int.bahn.de/en
Train from Mainz Hbf to Basel SBB
- Ave. Duration
- 4h 38m
- Frequency
- 4 times a week
- Estimated price
- CHF 60–240
- Website
- https://int.bahn.de/en
- Phone
- +49 621 830 1200
- Website
- suewex.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- CHF 13–19
- Schedules at
- suewex.de
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- CHF 12–19
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Once daily
- Estimated price
- CHF 7–16
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- CHF 26–55
- Website
- https://www.ns.nl/en
Train from Mainz Hbf to Basel SBB
- Ave. Duration
- 4h 38m
- Frequency
- Once daily
- Estimated price
- CHF 35–80
- Website
- https://www.ns.nl/en
- Phone
- +43 (0) 5 1717
- Website
- oebb.at
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 59m
- Frequency
- 4 times a week
- Estimated price
- CHF 50–90
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- CHF 60–180
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- CHF 60–180
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- CHF 60–180
- Website
- https://www.sbb.ch/en
Train from Zürich Flughafen to Nyon
- Ave. Duration
- 3h 13m
- Frequency
- Hourly
- Estimated price
- CHF 90–270
- Website
- https://www.sbb.ch/en
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Frankfurt Airport to Geneva
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- CHF 40–75
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Frankfurt Airport to Geneva
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- CHF 45–85
- Website
- https://www.blablacar.co.uk/bus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Mainz to Nyon bus services, operated by FlixBus, arrive at Geneva station.
Mainz to Nyon train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Nyon is 546 km. It takes approximately 5h 3m to drive from Mainz to Nyon.
Book your Mainz to Nyon train tickets online with Omio.
There are 1565+ hotels available in Nyon.



































