There are 8 ways to get from Mainz to Nyon by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Geneva International Airport
best- Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane FRA - GVA
4h 22mCHF 113–286Bus
cheapest- Take the bus from Frankfurt Airport to Genevabus FlixBus N122
11h 32mCHF 56–95Train
- Take the train from Frankfurt to Basel SBBtrain 43
- Take the train from Basel SBB to Renens VDtrain Ic51
7h 17mCHF 89–234Drive 546 km
- Drive from Mainz to Nyoncar 546 km
5h 3mCHF 105–151Fly to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)plane FRA - BSL
- Take the train from Basel SBB to Renens VDtrain
6h 9mCHF 170–455Fly to Zurich Airport, train
- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane FRA - ZRH
- Take the train from Zürich Flughafen to Nyontrain
6h 16mCHF 175–353Train via Mannheim
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Renens VDtrain
7h 26mCHF 92–241Train #2
- Take the train from Mainz Hbf to Basel SBBtrain Nightjet
- Take the train from Basel SBB to Renens VDtrain Ic51
8h 6mCHF 91–216
Mainz to Nyon by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Nyon is to bus which costs SFr 55 - SFr 95 and takes 11h 32m.
The fastest way to get from Mainz to Nyon is to fly which takes 4h 22m and costs SFr 110 - SFr 290.
No, there is no direct bus from Mainz to Nyon. However, there are services departing from Mainz, Hauptbahnhof and arriving at Geneva via Frankfurt Airport. The journey, including transfers, takes approximately 11h 32m.
No, there is no direct train from Mainz to Nyon. However, there are services departing from Mainz, Römisches Theater and arriving at Nyon via Frankfurt, Basel SBB and Renens VD. The journey, including transfers, takes approximately 7h 17m.
The distance between Mainz and Nyon is 518 km. The road distance is 546 km.
The best way to get from Mainz to Nyon without a car is to train which takes 7h 17m and costs SFr 85 - SFr 240.
It takes approximately 4h 22m to get from Mainz to Nyon, including transfers.
Mainz to Nyon bus services, operated by FlixBus, depart from Frankfurt Airport station.
Mainz to Nyon train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Nyon is to fly which takes 4h 22m and costs SFr 110 - SFr 290. Alternatively, you can train, which costs SFr 85 - SFr 240 and takes 7h 17m, you could also bus, which costs SFr 55 - SFr 95 and takes 11h 32m.
What companies run services between Mainz, Germany and Nyon, Switzerland?
Lufthansa, Air Dolomiti, and two other airlines fly from Frankfurt (FRA) to Geneva International Airport (GVA) every 3 hours. Alternatively, you can take a train from Mainz, Römisches Theater to Nyon via Frankfurt, Basel SBB, and Renens VD in around 7h 17m.
- Website
- lufthansa.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- CHF 90–400
Flights from Frankfurt to Geneva International Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- CHF 90–210
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–420
Flights from Frankfurt to Basel via Munich
- Ave. Duration
- 2h 50m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- CHF 75–260
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 70–380
- Website
- swiss.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- CHF 90–400
Flights from Frankfurt to Geneva International Airport via Zurich Airport
- Ave. Duration
- 2h 53m
- When
- Every day
- Estimated price
- CHF 90–410
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–260
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 70–380
- Website
- airdolomiti.it
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 140–400
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 140–420
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 130–380
- Website
- condor.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- CHF 90–200
- Website
- brusselsairlines.com
Flights from Frankfurt to Geneva International Airport via Brussels
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- CHF 130–280
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Estimated price
- CHF 50–110
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- CHF 35–80
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz Hbf to Basel SBB
- Ave. Duration
- 4h 38m
- Frequency
- Once a week
- Estimated price
- CHF 55–120
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- CHF 30–60
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- CHF 25–50
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz Hbf to Basel SBB
- Ave. Duration
- 4h 38m
- Frequency
- Once daily
- Estimated price
- CHF 35–70
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- CHF 50–85
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- CHF 50–85
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich Flughafen to Nyon
- Ave. Duration
- 3h 13m
- Frequency
- Hourly
- Estimated price
- CHF 80–130
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- CHF 50–85
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- CHF 50–85
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- CHF 13–60
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Twice daily
- Estimated price
- CHF 13–19
- Schedules at
- Süwex
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Frankfurt Airport to Geneva
- Ave. Duration
- 8h 55m
- Frequency
- 5 times a week
- Estimated price
- CHF 45–75
- Website
- Flixbus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Booking & Getting There
Mainz to Nyon bus services, operated by FlixBus, arrive at Geneva station.
Mainz to Nyon train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Mainz to Nyon is 546 km. It takes approximately 5h 3m to drive from Mainz to Nyon.
Book your Mainz to Nyon train tickets online with Omio.
Book your Mainz to Nyon bus tickets online with Omio.
There are 1480+ hotels available in Nyon.























