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How to get fromMainz to Pilsenby bus, train, night train, car or plane

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There are 6 ways to get from Mainz to Pilsen by bus, train, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Frankfurt Central Train Station to Pilsen Central Bus StationbusRegioJet 540
    6h 35m
    Kč 742–1,195
  2. Train

    1. Take the train from Frankfurt to Nürnberg Hbftrain41 / ...
    2. Take the train from Nürnberg Hbf to Schwandorftrain
    3. Take the train from Schwandorf to Plzen Hlavni NadrazitrainRe
    8h 5m
    Kč 2,164–3,550
  3. Night train, train

    1. Take the night train from Mainz Hbf to Regensburg HbfnighttrainNj
    2. Take the train from Regensburg Hbf to Plzen Hlavni NadrazitrainRe
    7h 26m
    Kč 2,271–7,602
  4. Drive 447.7 km

    1. Drive from Mainz to Pilsencar447.7 km
    3h 49m
    Kč 1,667–2,408
  5. Bus via Mainz, Römisches Theater

    1. Take the bus from Frankfurt central train station to Plzeňbus084
    8h 10m
    Kč 816–1,452
  6. Fly, bus

    1. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)planeFRA - PRG
    2. Take the bus from Prague to Plzeňbus
    5h 29m
    Kč 1,820–3,733

Mainz to Pilsen by bus

Calendar7Weekly Buses
Duration6h 35mAverage Duration
TicketKč 742Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Pilsen, Czechia?

RegioJet operates a bus from Frankfurt Central Train Station to Pilsen Central Bus Station once daily. Tickets cost Kč 600–1,000 and the journey takes 4h 55m. Alternatively, you can take a train from Mainz, Römisches Theater to Plzen Hlavni Nadrazi via Frankfurt, Nürnberg Hbf, and Schwandorf in around 8h 5m.

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