There are 8 ways to get from Mainz to Milan by plane, train, bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Milan Linate Airport
best- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane FRA - LIN
3h 47m€41–173Train
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
9h 14m€83–343Bus
- Take the bus from Mainz central train station to Milanbus FlixBus 476
12h 36m€67–99Night train, train
- Take the nighttrain from Mainz Hbf to Zuerich Hbnighttrain Nj
- Take the train from Zürich HB to Como S. Giovannitrain Ec
- Take the train from Como S.Giovanni to Milano Porta Garibalditrain S11
11h 13m€111–258Fly Frankfurt to Milano Malpensa Airport, train
- Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane FRA - MXP
- Take the train from Malpensa Aeroporto T1 to Milano Porta Garibalditrain
4h 41m€64–206Train to Stuttgart Airport, fly to Milan Linate Airport
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Milan Linate Airport (LIN)plane STR - LIN
5h 36m€135–375Train, bus
- Take the train from Mainz Hbf to Zürich HBtrain Nightjet
- Take the bus from Zürich to Milano, Autostazione Lampugnanobus BlaBlaCar Bus
11h 6m€70–131Drive 662.1 km
- Drive from Mainz to Milancar 662.1 km
6h 16m€107–155
Mainz to Milan by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Milan is to bus which costs €65 - €100 and takes 12h 36m.
The fastest way to get from Mainz to Milan is to fly which takes 3h 47m and costs €40 - €180.
No, there is no direct bus from Mainz station to Milan. However, there are services departing from Mainz central train station and arriving at Milano, Autostazione Lampugnano via via omodeo via cechov. The journey, including transfers, takes approximately 12h 36m.
No, there is no direct train from Mainz to Milan. However, there are services departing from Mainz, Hauptbahnhof and arriving at Milano Centrale via Mannheim, Hauptbahnhof, Basel SBB and Lugano. The journey, including transfers, takes approximately 9h 14m.
The distance between Mainz and Milan is 547 km. The road distance is 662.1 km.
The best way to get from Mainz to Milan without a car is to train which takes 9h 14m and costs €80 - €350.
It takes approximately 3h 47m to get from Mainz to Milan, including transfers.
Mainz to Milan bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Milan train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Milan is to fly which takes 3h 47m and costs €40 - €180. Alternatively, you can train, which costs €80 - €350 and takes 9h 14m, you could also bus, which costs €65 - €100 and takes 12h 36m.
What companies run services between Mainz, Germany and Milan, Italy?
easyJet, Lufthansa, and Air Dolomiti fly from Frankfurt (FRA) to Milan Linate Airport (LIN) every 4 hours. Alternatively, you can take a train from Mainz, Hauptbahnhof to Milano Centrale via Mannheim, Hauptbahnhof, Basel SBB, and Lugano in around 9h 14m.
- Website
- lufthansa.com
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–440
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €75–380
Flights from Frankfurt to Milano Malpensa Airport via Munich
- Ave. Duration
- 3h 13m
- When
- Every day
- Estimated price
- €75–400
Flights from Stuttgart Airport to Milan Linate Airport via Munich
- Ave. Duration
- 2h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €130–310
- Website
- airdolomiti.it
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–440
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €120–380
- Website
- condor.com
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €55–160
- Website
- easyjet.com
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–140
- Website
- swiss.com
Flights from Frankfurt to Milano Malpensa Airport via Zurich
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- €75–190
- Website
- eurowings.com
Flights from Stuttgart Airport to Milan Linate Airport
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €90–260
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €12–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €40–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- €30–70
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €13–55
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €14–20
- Schedules at
- Süwex
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Twice daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- €27–55
- Website
- Nederlandse Spoorwegen (NS)
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- Once daily
- Estimated price
- €50–100
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz Hbf to Zürich HB
- Ave. Duration
- 6h 22m
- Frequency
- Twice daily
- Estimated price
- €50–100
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €90–150
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €28–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Como S. Giovanni
- Ave. Duration
- 2h 35m
- Frequency
- Hourly
- Estimated price
- €75–130
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Como S.Giovanni to Milano Porta Garibaldi
- Ave. Duration
- 1h 2m
- Frequency
- Once daily
- Estimated price
- €17–28
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- 3 times a week
- Estimated price
- €30–101
- Website
- Nightjet
- Sleeper Carriage
- €97–101
- Couchette Carriage
- €60–75
- Seating Carriage
- €30–40
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Train from Como S.Giovanni to Milano Porta Garibaldi
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Milano Porta Garibaldi
- Ave. Duration
- 44 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Mainz central train station to Milan
- Ave. Duration
- 12h 5m
- Frequency
- Once daily
- Estimated price
- €65–100
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Zürich to Milano, Autostazione Lampugnano
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- €20–35
- Website
- BlaBlaCar Bus
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Getting to Milan from the airport
Read the travel guide
Booking & Getting There
Mainz to Milan bus services, operated by FlixBus, arrive at Milan station.
Mainz to Milan train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Milan is 662 km. It takes approximately 6h 16m to drive from Mainz to Milan.
Book your Mainz to Milan train tickets online with Omio.
Book your Mainz to Milan bus tickets online with Omio.
There are 13827+ hotels available in Milan.












































