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How to get fromIowa to Lexingtonby plane, bus, car, or train

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There are 9 ways to get from Iowa to Lexington by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Blue Grass Airport

    best
    1. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    6h 52m
    $250–1,223

  2. Drive 648.5 mi

    cheapest
    1. Drive from Des Moines to Lexingtoncar car 648.5 mi
    11h 15m
    $119–171

  3. Bus

    1. Take the bus from Des Moines to Indianapolisbus bus Btw 1402
    2. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus Greyhound US0120
    14h 32m

  4. Fly Waterloo Municipal Airport to Blue Grass Airport

    1. Fly from Waterloo Municipal Airport (ALO) to Blue Grass Airport (LEX)plane plane ALO - LEX
    7h 50m
    $152–776

  5. Fly The Eastern Iowa Airport to Blue Grass Airport

    1. Fly from The Eastern Iowa Airport (CID) to Blue Grass Airport (LEX)plane plane CID - LEX
    8h 21m
    $267–1,432

  6. Fly Quad City International Airport to Blue Grass Airport

    1. Fly from Quad City International Airport (MLI) to Blue Grass Airport (LEX)plane plane MLI - LEX
    8h 33m
    $124–704

  7. Bus to Chicago Midway International Airport, fly to Louisville International Airport, drive

    1. Take the bus from Davenport to Chicagobus bus
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 39m

  8. Fly Omaha to Blue Grass Airport

    1. Fly from Omaha (OMA) to Blue Grass Airport (LEX)plane plane OMA - LEX
    9h 29m
    $205–1,005

  9. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    19h 21m

Des Moines (DSM) to Blue Grass Airport (LEX) flights

Calendar99Weekly Planes
Duration6h 5mAverage Duration
Ticket$229Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Lexington.ExpandLaunch map view
  • Distance: 558.2 mi
  • Duration: 6h 52m

What companies run services between Iowa, USA and Lexington, KY, USA?

United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to Blue Grass Airport (LEX) hourly. Alternatively, you can take a bus from Des Moines to Lexington via Indianapolis Union Station and Lexington Bus Stop in around 14h 32m.

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