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How to get fromIowa to Illinoisby bus, plane, bus (Greyhound), car, or train

Find Transport to Illinois

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There are 4 ways to get from Iowa to Illinois by bus, plane, bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 60 bus, fly

    best
    1. Take the bus from District to SouthPark Mall Shelterbus bus
    2. Fly from Quad City International Airport (MLI) to Chicago O'Hare International Airport (ORD)plane plane MLI - ORD
    4h 12m
    $32–217

  2. Bus (Greyhound)

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    7h 10m
    $59–105

  3. Drive 330.7 mi

    1. Drive from Des Moines to Chicagocar car 330.7 mi
    5h 33m
    $61–88

  4. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus Greyhound US0157S
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train Carl Sandburg / ...
    8h 30m
    $89–180

Quad City International Airport (MLI) to Chicago O'Hare International Airport (ORD) flights

Calendar90Weekly Planes
Duration1h 19mAverage Duration
Ticket$28Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Illinois.ExpandLaunch map view
  • Distance: 169.6 mi
  • Duration: 4h 12m

What companies run services between Iowa, USA and Illinois, USA?

Greyhound USA operates a bus from Des Moines to Chicago Bus Station 3 times a day. Tickets cost $50–95 and the journey takes 7h 5m.

Airlines
Train operators
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