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How to get fromIowa to Illinoisby bus, plane, bus (Greyhound), car or train

Find Transport to Illinois

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There are 6 ways to get from Iowa to Illinois by bus, plane, bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 60 bus, fly

    best
    1. Take the bus from District to SouthPark Mall Shelterbus bus
    2. Fly from Quad City International Airport (MLI) to Chicago O'Hare International Airport (ORD)plane plane MLI - ORD
    4h 13m
    $34–227
  2. Bus via Des Moines (Greyhound)

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    7h 10m
    $64–110
  3. Drive 330.7 mi

    1. Drive from Des Moines to Chicagocar car 330.7 mi
    5h 30m
    $61–88
  4. Bus

    1. Take the bus from Des Moines to Chicagobus bus Des Moines
    7h 15m
    $55–160
  5. Bus #2

    1. Take the bus from Des Moines to Chicagobus bus Omaha
    7h 28m
    $67–152
  6. Bus, train

    1. Take the bus from Des Moines to Burlingtonbus bus
    2. Take the bus from Burlington to Galesburgbus bus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    8h 55m
    $90–207

Iowa to Illinois by bus

Calendar14Weekly Buses
Duration7h 15mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Illinois, USA?

Greyhound USA operates a bus from Des Moines to Chicago Bus Station 3 times a day. Tickets cost $55–100 and the journey takes 7h 5m.

Airlines
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Need to know: Greyhound

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