Rome2Rio

How to get fromSt. Louis to Lexingtonby bus, car or plane

Find Transport to Lexington

See all options

There are 5 ways to get from St. Louis to Lexington by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive

    best
    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville, IN to Louisville, KYbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    10h 31m
    $77–116

  2. Drive 337.8 mi

    cheapest
    1. Drive from St. Louis to Lexingtoncar car 337.8 mi
    5h 44m
    $62–90

  3. Fly to Covington, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)plane plane STL - CVG
    2. Drive from Covington (CVG) to Lexingtoncar car
    6h 41m
    $168–974

  4. Fly to Louisville International Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)plane plane STL - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 15m
    $126–774

  5. Fly to Blue Grass Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)plane plane STL - LEX
    7h 45m
    $94–554

Lambert–St. Louis International Airport (STL) to Covington (CVG) flights

Calendar135Weekly Planes
Duration4h 57mAverage Duration
Ticket$156Cheapest Price
See schedules

Questions & Answers

What companies run services between St. Louis, MO, USA and Lexington, KY, USA?

American Airlines, Delta, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX) every 2 hours.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from St. Louis

Trips to Lexington

Popular routes