There are 8 ways to get from Iowa to Kentucky by plane, bus (Greyhound, Amtrak), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Des Moines to Louisville International Airport
best- Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane DSM - SDF
4h 56m$139–724Fly Quad City International Airport to Louisville International Airport
cheapest- Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane MLI - SDF
7h 53m$73–435Bus
- Take the bus from Des Moines to Indianapolis Union Stationbus Greyhound US0157S
- Take the bus from Indianapolis Union Station to Louisville, KYbus Chicago
13h 30m$101–195Bus, train
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
18h 4m$161–340Drive 579.9 mi
- Drive from Des Moines to Louisvillecar 579.9 mi
9h 44m$106–153Fly Quad City International Airport to Covington
- Fly from Quad City International Airport (MLI) to Covington (CVG)plane MLI - CVG
6h 38m$84–554Fly Omaha to Louisville International Airport
- Fly from Omaha (OMA) to Louisville International Airport (SDF)plane OMA - SDF
7h 29m$134–756Bus via Speedway
- Take the bus from Des Moines to Indianapolis Union Stationbus Greyhound US0157S
- Take the bus from Indianapolis to El Mercadito Grocery - Clarksville, INbus Indianapolis
15h 37m$127–295
Des Moines (DSM) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Iowa to Kentucky is to bus which costs $100 - $200 and takes 13h 30m.
The fastest way to get from Iowa to Kentucky is to fly which takes 4h 56m and costs $130 - $750.
The distance between Iowa and Kentucky is 495 miles. The road distance is 583.3 miles.
The best way to get from Iowa to Kentucky without a car is to bus which takes 13h 30m and costs $100 - $200.
It takes approximately 4h 56m to get from Iowa to Kentucky, including transfers.
The best way to get from Iowa to Kentucky is to fly which takes 4h 56m and costs $130 - $750. Alternatively, you can bus, which costs $100 - $200 and takes 13h 30m.
Kentucky is 1h ahead of Iowa. It is currently 8:32 AM in Iowa and 9:32 AM in Kentucky.
Yes, the driving distance between Iowa to Kentucky is 583 miles. It takes approximately 9h 44m to drive from Iowa to Kentucky.
There are 266+ hotels available in Kentucky.
What companies run services between Iowa, USA and Kentucky, USA?
Southwest Airlines, United Airlines, and three other airlines fly from Des Moines (DSM) to Louisville International Airport (SDF) hourly. Alternatively, you can take a vehicle from Des Moines to Louisville, KY via Des Moines and Indianapolis Union Station in around 13h 30m.
- Website
- delta.com
Flights from Des Moines to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $190–950
Flights from Des Moines to Louisville International Airport via Detroit
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $160–850
Flights from Des Moines to Louisville International Airport via Minneapolis
- Ave. Duration
- 7h 16m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
Flights from Quad City International Airport to Covington via Atlanta
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $150–750
Flights from Quad City International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $120–600
Flights from Omaha to Louisville International Airport via Minneapolis
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $160–850
Flights from Omaha to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $200–950
Flights from Omaha to Louisville International Airport via Detroit
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $170–850
- Website
- aa.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $120–750
Flights from Des Moines to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $210–950
Flights from Quad City International Airport to Covington via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $80–550
Flights from Quad City International Airport to Covington via Charlotte
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $150–750
Flights from Quad City International Airport to Covington via Dallas/Ft.Worth
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $210–900
Flights from Quad City International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $120–600
Flights from Quad City International Airport to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $160–750
Flights from Quad City International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $70–430
Flights from Omaha to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $140–750
Flights from Omaha to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 58m
- When
- Every day
- Estimated price
- $210–1,000
- Website
- united.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $120–750
Flights from Quad City International Airport to Covington via Chicago O'Hare
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $80–550
Flights from Quad City International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $70–430
Flights from Omaha to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $140–750
- Website
- southwest.com
Flights from Des Moines to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 32m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $120–700
Flights from Omaha to Louisville International Airport via Chicago Midway
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $130–750
Flights from Omaha to Louisville International Airport via Nashville
- Ave. Duration
- 4h 18m
- When
- Saturday, Sunday, and Monday
- Estimated price
- $140–800
- Website
- allegiantair.com
Flights from Des Moines to Louisville International Airport via Valparaiso
- Ave. Duration
- 5h 38m
- When
- Saturday
- Estimated price
- $240–1,100
Flights from Quad City International Airport to Covington via Orlando Sanford
- Ave. Duration
- 7h 58m
- When
- Saturday
- Estimated price
- $240–1,000
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $45–100
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $55–120
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.greyhound.com/
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Indianapolis to El Mercadito Grocery - Clarksville, IN
- Ave. Duration
- 2h 19m
- Frequency
- 3 times a week
- Estimated price
- $45–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–140
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