There are 8 ways to get from Iowa to Kentucky by plane, bus (Greyhound, Amtrak), car, bus, train, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Des Moines to Louisville International Airport
best- Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane DSM - SDF
5h 6m$169–924Fly Quad City International Airport to Louisville International Airport
cheapest- Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane MLI - SDF
7h 22m$78–485Bus
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
- Take the bus from Chicago Union Station to Louisville, KYbus Chicago
15h 19m$109–170Drive 579.9 mi
- Drive from Des Moines to Louisvillecar 579.9 mi
9h 44m$106–153Fly Quad City International Airport to Covington
- Fly from Quad City International Airport (MLI) to Covington (CVG)plane MLI - CVG
6h 50m$99–654Fly Omaha to Louisville International Airport
- Fly from Omaha (OMA) to Louisville International Airport (SDF)plane OMA - SDF
7h 36m$154–856Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
16h 38m$121–255Bus via Speedway
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Indianapolisbus
- Take the bus from Indianapolis to El Mercadito Grocery - Clarksville, INbus
17h 19m$128–295
Des Moines (DSM) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Iowa to Kentucky is to drive which costs $100 - $160 and takes 9h 44m.
The fastest way to get from Iowa to Kentucky is to fly which takes 5h 6m and costs $160 - $950.
The distance between Iowa and Kentucky is 495 miles. The road distance is 583.3 miles.
The best way to get from Iowa to Kentucky without a car is to bus which takes 15h 19m and costs $100 - $170.
It takes approximately 5h 6m to get from Iowa to Kentucky, including transfers.
The best way to get from Iowa to Kentucky is to fly which takes 5h 6m and costs $160 - $950. Alternatively, you can bus, which costs $100 - $170 and takes 15h 19m.
Kentucky is 1h ahead of Iowa. It is currently 8:25 AM in Iowa and 9:25 AM in Kentucky.
Yes, the driving distance between Iowa to Kentucky is 583 miles. It takes approximately 9h 44m to drive from Iowa to Kentucky.
There are 600+ hotels available in Kentucky.
What companies run services between Iowa, USA and Kentucky, USA?
Southwest Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to Louisville International Airport (SDF) hourly. Alternatively, you can take a vehicle from Des Moines to Louisville, KY via Des Moines, Chicago Bus Station, and Chicago Union Station in around 15h 19m.
- Website
- aa.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $150–950
Flights from Des Moines to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Quad City International Airport to Covington via Chicago O'Hare
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $95–650
Flights from Quad City International Airport to Covington via Charlotte
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $160–850
Flights from Quad City International Airport to Covington via Dallas/Ft.Worth
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Quad City International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $75–480
Flights from Quad City International Airport to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $160–750
Flights from Quad City International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 7h 47m
- When
- Every day
- Estimated price
- $120–650
Flights from Omaha to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–850
Flights from Omaha to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $220–1,100
- Website
- delta.com
Flights from Des Moines to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Des Moines to Louisville International Airport via Minneapolis
- Ave. Duration
- 6h 46m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Des Moines to Louisville International Airport via Detroit
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Quad City International Airport to Covington via Atlanta
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $160–850
Flights from Quad City International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $120–650
Flights from Omaha to Louisville International Airport via Minneapolis
- Ave. Duration
- 5h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–950
Flights from Omaha to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Omaha to Louisville International Airport via Detroit
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $180–950
- Website
- united.com
Flights from Des Moines to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $150–950
Flights from Quad City International Airport to Covington via Chicago O'Hare
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $95–650
Flights from Quad City International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $75–480
Flights from Omaha to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $150–850
- Website
- southwest.com
Flights from Des Moines to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- $150–900
Flights from Omaha to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $150–850
Flights from Omaha to Louisville International Airport via Nashville
- Ave. Duration
- 6h 17m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–900
Flights from Omaha to Louisville International Airport via Dallas
- Ave. Duration
- 6h 25m
- When
- Sunday
- Estimated price
- $230–1,100
- Website
- allegiantair.com
Flights from Quad City International Airport to Covington via St. Petersburg
- Ave. Duration
- 8h 3m
- When
- Thursday and Sunday
- Estimated price
- $260–1,200
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $40–100
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 7h
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- https://www.amtrak.com/home.html
- Adult
- $50–60
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Indianapolis
- Ave. Duration
- 3h 50m
- Frequency
- Every 4 hours
- Estimated price
- $21–40
- Schedules at
- flixbus.com
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Indianapolis to El Mercadito Grocery - Clarksville, IN
- Ave. Duration
- 2h 19m
- Frequency
- 3 times a week
- Estimated price
- $45–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–140
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