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How to get fromEffingham to BuffaloBy bus (Greyhound), train (Amtrak), car, plane, or train

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There are 6 ways to get from Effingham to Buffalo by bus (Greyhound), train (Amtrak), car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Toledo

    best
    1. Take the bus from Effingham to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis, IN to Toledobus bus
    3. Take the bus from Toledo to Clevelandbus bus
    4. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    14h 30m
    $73–209

  2. Train (Amtrak)

    1. Take the train from Effingham Station to Chicago Union Stationtrain train Saluki / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    16h 35m
    $203–502

  3. Drive 636.5 mi

    1. Drive from Effingham to Buffalocar car 636.5 mi
    10h 58m
    $117–168

  4. Drive to Decatur Airport, fly

    1. Drive from Effingham to Decatur Airport (DEC)car car
    2. Fly from Decatur Airport (DEC) to Buffalo Niagara International Airport (BUF)plane plane DEC - BUF
    8h 51m
    $216–1,244

  5. Bus

    1. Take the bus from Effingham to Pittsburgh Intermodal Stationbus bus Greyhound US0421
    2. Take the bus from Pittsburgh to Buffalobus bus Fab510
    21h 20m
    $122–335

  6. Train to University Of Illinois Willard Airport, fly

    1. Take the train from Effingham Station to Champaign-Urbanatrain train
    2. Fly from University Of Illinois Willard Airport (CMI) to Buffalo Niagara International Airport (BUF)plane plane CMI - BUF
    9h 38m
    $232–1,192

Effingham to Buffalo by bus

Calendar7Weekly Buses
Duration14h 30mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

What companies run services between Effingham, IL, USA and Buffalo, NY, USA?

You can take a bus from Effingham to Buffalo, NY via Indianapolis, IN, Toledo, and Cleveland, OH in around 14h 30m. Alternatively, you can take a train from Effingham Station to Buffalo via Chicago Union Station and Buffalo Depew Station in around 16h 35m.

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