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How to get fromMilwaukee to Buffaloby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train or bus (Flixbus, Greyhound)

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There are 7 ways to get from Milwaukee to Buffalo by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Mitchell International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Buffalo Niagara International Airport (BUF)planeMKE - BUF
    6h 11m
    $276–1,760

  2. Bus

    cheapest
    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
    2. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus
    3. Take the bus from Cleveland Bus Station to Buffalobus
    14h 45m
    $68–206

  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union StationtrainHiawatha Service / ...
    2. Take the train from Chicago Union Station to Buffalo Depew StationtrainLake Shore Limited
    14h 13m
    $86–324

  4. Drive 620.9 mi

    1. Drive from Milwaukee to Buffalocar620.9 mi
    10h 36m
    $114–164

  5. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)planeORD - BUF
    5h 31m
    $189–1,018

  6. Train to Chicago Midway International Airport, fly

    1. Take the train from Milwaukee to Chicago Union Stationtrain
    2. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)planeMDW - BUF
    5h 56m
    $218–1,224

  7. Bus via Detroit

    1. Take the bus from Milwaukee Intermodal Station to Detroit Bus Stationbus
    2. Take the bus from Detroit Bus Station to Torontobus
    3. Take the bus from Toronto to Buffalobus
    18h 53m
    $103–277

Milwaukee to Buffalo by train (Amtrak)

Calendar14Weekly Trains
Duration14h 13mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

What companies run services between Milwaukee, WI, USA and Buffalo, NY, USA?

Delta, Southwest Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a train from Milwaukee to Buffalo via Chicago Union Station and Buffalo Depew Station in around 14h 13m.

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