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How to get fromEffingham to Lexingtonby bus, car, train, or plane

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There are 6 ways to get from Effingham to Lexington by bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive

    best
    1. Take the bus from Effingham to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    9h 32m
    $57–109

  2. Drive 265.4 mi

    cheapest
    1. Drive from Effingham to Lexingtoncar car 265.4 mi
    5h 38m
    $49–70

  3. Train, fly

    1. Take the train from Effingham Station to Champaign-Urbanatrain train
    2. Fly from University Of Illinois Willard Airport (CMI) to Blue Grass Airport (LEX)plane plane CMI - LEX
    9h 2m
    $162–820

  4. Bus, drive via Louisville

    1. Take the bus from Effingham to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    10h 42m
    $56–106

  5. Bus, drive via Louisville #2

    1. Take the bus from Effingham to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    10h 49m
    $56–106

  6. Bus, drive via Speedway

    1. Take the bus from Effingham to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis to El Mercadito Grocery - Clarksville, INbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    11h 4m
    $81–203

University Of Illinois Willard Airport (CMI) to Blue Grass Airport (LEX) flights

Calendar41Weekly Planes
Duration6h 33mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Effingham to Lexington.ExpandLaunch map view
  • Distance: 345.1 mi
  • Duration: 9h 32m

What companies run services between Effingham, IL, USA and Lexington, KY, USA?

There is no direct connection from Effingham to Lexington. However, you can take the bus to Indianapolis Union Station, take the bus to Louisville, KY, walk to Liberty @ Roy Wilkins, take the line 72 bus to Liberty @ 6th, walk to S 5th @ W Jefferson, take the line 31 bus to Middletown Station @ Target, then drive to Lexington. Alternatively, you can drive from Effingham to Lexington in around 5h 38m.

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