There are 11 ways to get from Destin to Buffalo by plane, taxi, bus, train, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport
best- Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane VPS - BUF
5h 48m$257–1,330Fly Destin–Fort Walton Beach Airport to Rochester, bus
cheapest- Fly from Destin–Fort Walton Beach Airport (VPS) to Rochester (ROC)plane VPS - ROC
- Take the bus from Rochester, NY to Buffalo, NYbus
8h 18m$197–885Taxi, bus
- Take the taxi from Destin to Crestviewtaxi
- Take the bus from Crestview to Tallahasseebus
- Take the bus from Tallahassee to Nashville Bus Stationbus
- Take the bus from Nashville Bus Station to Cleveland Bus Stationbus
- Take the bus from Cleveland, OH to Buffalo, NYbus
31h 52m$274–522Taxi, bus, train via New York
- Take the taxi from Destin to Whataburger - Defuniak Springstaxi
- Take the bus from Whataburger - Defuniak Springs to Circle K - Gainesville, FLbus
- Take the bus from Gainesville to Orlando Bus Stationbus
- Take the train from Orlando to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain
40h 34m$416–1,076Drive 1,150.7 mi
- Drive from Destin to Buffalocar 1,150.7 mi
19h 39m$210–304Taxi to Northwest Florida Beaches International Airport, fly to Buffalo Niagara International Airport
- Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi
- Fly from Northwest Florida Beaches International Airport (ECP) to Buffalo Niagara International Airport (BUF)plane ECP - BUF
6h 31m$340–1,429Taxi to Pensacola International Airport, fly to Buffalo Niagara International Airport
- Take the taxi from Destin to Pensacola-Airport-PNStaxi
- Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)plane PNS - BUF
7h 2m$382–1,532Fly Destin–Fort Walton Beach Airport to Toronto Pearson International Airport, shuttle
- Fly from Destin–Fort Walton Beach Airport (VPS) to Toronto Pearson International Airport (YYZ)plane VPS - YYZ
- Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airport
8h 43m$207–620Drive to Dothan Regional Airport, fly to Buffalo Niagara International Airport
- Drive from Destin to Dothan Regional Airport (DHN)car
- Fly from Dothan Regional Airport (DHN) to Buffalo Niagara International Airport (BUF)plane DHN - BUF
7h 54m$225–1,210Taxi, bus via Atlanta
- Take the taxi from Destin to McDonald's - Crestviewtaxi
- Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus
- Take the bus from Mobile to Atlantabus
- Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus
- Take the bus from Cleveland, OH to Buffalo, NYbus
32h 7m$312–583Taxi, bus, train
- Take the taxi from Destin to Crestviewtaxi
- Take the bus from Crestview to Wildwoodbus
- Take the bus from Wildwood Amtrak Station to Jacksonvillebus
- Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain
- Take the bus from Pittsburgh to Buffalobus
46h 53m
Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) flights
Questions & Answers
The cheapest way to get from Destin to Buffalo is to drive which costs $210 - $310 and takes 19h 39m.
The fastest way to get from Destin to Buffalo is to fly which takes 5h 48m and costs $250 - $1,400.
The distance between Destin and Buffalo is 992 miles. The road distance is 1157.4 miles.
The best way to get from Destin to Buffalo without a car is to taxi and bus which takes 31h 52m and costs $270 - $550.
It takes approximately 5h 48m to get from Destin to Buffalo, including transfers.
Buffalo is 1h ahead of Destin. It is currently 12:53 PM in Destin and 1:53 PM in Buffalo.
Yes, the driving distance between Destin to Buffalo is 1157 miles. It takes approximately 19h 39m to drive from Destin to Buffalo.
There are 219+ hotels available in Buffalo.
What companies run services between Destin, FL, USA and Buffalo, NY, USA?
Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) 5 times a day.
- Website
- delta.com
Flights from Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $210–1,200
Flights from Northwest Florida Beaches International Airport to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $210–1,200
Flights from Northwest Florida Beaches International Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $260–1,300
Flights from Pensacola International Airport to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 5h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,300
Flights from Pensacola International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 9h 42m
- When
- Friday to Sunday
- Estimated price
- $270–1,400
Flights from Destin–Fort Walton Beach Airport to Rochester via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $130–700
Flights from Destin–Fort Walton Beach Airport to Rochester via Detroit
- Ave. Duration
- 9h 47m
- When
- Saturday
- Estimated price
- $140–700
Flights from Destin–Fort Walton Beach Airport to Toronto Pearson International Airport via Atlanta
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $70–370
Flights from Destin–Fort Walton Beach Airport to Toronto Pearson International Airport via Detroit
- Ave. Duration
- 6h 3m
- When
- Saturday
- Estimated price
- $70–370
Flights from Dothan Regional Airport to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $200–1,100
- Website
- aa.com
Flights from Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 43m
- When
- Saturday
- Estimated price
- $230–1,200
Flights from Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Northwest Florida Beaches International Airport to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Northwest Florida Beaches International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 6h 36m
- When
- Saturday
- Estimated price
- $230–1,200
Flights from Northwest Florida Beaches International Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 8h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,300
Flights from Pensacola International Airport to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $260–1,400
Flights from Pensacola International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $270–1,400
Flights from Destin–Fort Walton Beach Airport to Rochester via Reagan Washington
- Ave. Duration
- 4h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Destin–Fort Walton Beach Airport to Rochester via Charlotte
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $130–700
- Website
- southwest.com
Flights from Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 4h 50m
- When
- Saturday
- Estimated price
- $220–1,200
Flights from Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 6h 55m
- When
- Thursday and Friday
- Estimated price
- $240–1,200
Flights from Northwest Florida Beaches International Airport to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 4h 25m
- When
- Saturday
- Estimated price
- $230–1,200
Flights from Northwest Florida Beaches International Airport to Buffalo Niagara International Airport via Chicago Midway
- Ave. Duration
- 6h 20m
- When
- Monday
- Estimated price
- $260–1,300
Flights from Pensacola International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 30m
- When
- Saturday
- Estimated price
- $270–1,400
Flights from Pensacola International Airport to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 5h 15m
- When
- Saturday and Sunday
- Estimated price
- $260–1,400
Flights from Destin–Fort Walton Beach Airport to Rochester via Baltimore
- Ave. Duration
- 6h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–700
- Website
- aircanada.com
Flights from Destin–Fort Walton Beach Airport to Toronto Pearson International Airport via Nashville
- Ave. Duration
- 4h 34m
- When
- Monday and Saturday
- Estimated price
- $70–370
Flights from Destin–Fort Walton Beach Airport to Toronto Pearson International Airport via Washington Dulles
- Ave. Duration
- 5h 56m
- When
- Saturday
- Estimated price
- $75–390
Flights from Destin–Fort Walton Beach Airport to Toronto Pearson International Airport via Pittsburgh
- Ave. Duration
- 6h 20m
- When
- Saturday
- Estimated price
- $70–370
- Website
- united.com
Flights from Destin–Fort Walton Beach Airport to Toronto Pearson International Airport via Nashville
- Ave. Duration
- 4h 34m
- When
- Monday and Saturday
- Estimated price
- $70–370
Flights from Destin–Fort Walton Beach Airport to Toronto Pearson International Airport via Washington Dulles
- Ave. Duration
- 5h 56m
- When
- Saturday
- Estimated price
- $75–390
Flights from Destin–Fort Walton Beach Airport to Toronto Pearson International Airport via Pittsburgh
- Ave. Duration
- 6h 20m
- When
- Saturday
- Estimated price
- $70–370
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Orlando to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 21h 42m
- Frequency
- Once daily
- Estimated price
- $140–550
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Buffalo
- Ave. Duration
- 8h 45m
- Frequency
- 3 times a day
- Estimated price
- $60–160
- Website
- https://www.amtrak.com/home.html
Train from Jacksonville to Pittsburgh Amtrak Station
- Ave. Duration
- 25h 19m
- Frequency
- Once daily
- Estimated price
- $130–500
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Crestview to Tallahassee
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $50–70
- Schedules at
- omnibusexpress.com
Bus from Mobile to Atlanta
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- $70–95
- Schedules at
- omnibusexpress.com
Bus from Crestview to Wildwood
- Ave. Duration
- 5h 52m
- Frequency
- Once daily
- Estimated price
- $75–95
- Schedules at
- omnibusexpress.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Tallahassee to Nashville Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- https://www.greyhound.com/
Bus from Nashville Bus Station to Cleveland Bus Station
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $65–170
- Website
- https://www.greyhound.com/
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $27–55
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Cleveland Bus Station
- Ave. Duration
- 18h 5m
- Frequency
- Once daily
- Estimated price
- $85–180
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Whataburger - Defuniak Springs to Circle K - Gainesville, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $60–170
- Schedules at
- tornadobus.com
- Adults 11-59
- $60–170
Bus from McDonald's - Crestview to Love's Travel Stop - Loxley
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $40–130
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–130
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Gainesville to Orlando Bus Station
- Ave. Duration
- 2h
- Frequency
- Every 4 hours
- Estimated price
- $26–40
- Schedules at
- flixbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Rochester, NY to Buffalo, NY
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
- Phone
- 905-374-8111
- airsales@niagaraairbus.com
- Website
- niagaraairbus.com
Shuttle from Pearson International Airport Terminal 1 to Buffalo Airport
- Ave. Duration
- 2h
- Frequency
- On demand
- Estimated price
- $90–120
- Website
- https://www.niagaraairbus.com
- Schedules at
- https://www.niagaraairbus.com
- Book at
- https://www.niagaraairbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Wildwood Amtrak Station to Jacksonville
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 814-574-1827
- Website
- fullingtontours.com
Bus from Pittsburgh to Buffalo
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $110–150
- Website
- https://www.fullingtontours.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Pittsburgh to Buffalo
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $40–180
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $40–170
- Flexible
- $80–180
- Ave. Duration
- 56 min
- Estimated price
- $75–160
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
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