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How to get fromDestin to Buffaloby plane, taxi, bus, train, car, or shuttle

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There are 9 ways to get from Destin to Buffalo by plane, taxi, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane plane VPS - BUF
    5h 31m
    $235–1,029

  2. Drive 1,150.7 mi

    cheapest
    1. Drive from Destin to Buffalocar car 1,150.7 mi
    19h 38m
    $210–304

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus bus
    5. Take the bus from Cleveland Bus Station to Buffalobus bus
    32h 37m
    $321–527

  4. Taxi, bus, train via New York

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain train
    5. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    40h 58m
    $654–1,195

  5. Taxi to Northwest Florida Beaches International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Buffalo Niagara International Airport (BUF)plane plane ECP - BUF
    6h 14m
    $318–1,128

  6. Taxi to Pensacola International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)plane plane PNS - BUF
    6h 23m
    $320–1,081

  7. Fly Destin–Fort Walton Beach Airport to Rochester, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Rochester (ROC)plane plane VPS - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 31m
    $211–793

  8. Fly Destin–Fort Walton Beach Airport to Toronto Pearson International Airport, shuttle

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Toronto Pearson International Airport (YYZ)plane plane VPS - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    8h 28m
    $210–569

  9. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain train
    5. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    46h 41m
    $589–1,155

Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) flights

Calendar52Weekly Planes
Duration6h 2mAverage Duration
Ticket$196Cheapest Price
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Questions & Answers

Map of how to get from Destin to Buffalo.ExpandLaunch map view
  • Distance: 991.1 mi
  • Duration: 5h 31m

What companies run services between Destin, FL, USA and Buffalo, NY, USA?

Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) every 4 hours.

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