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How to get fromDestin to Buffaloby plane, taxi, bus, train, car or shuttle

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There are 11 ways to get from Destin to Buffalo by plane, taxi, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane plane VPS - BUF
    5h 48m
    $257–1,330

  2. Fly Destin–Fort Walton Beach Airport to Rochester, bus

    cheapest
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Rochester (ROC)plane plane VPS - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus bus
    8h 18m
    $197–885

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus bus
    5. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    31h 52m
    $274–522

  4. Taxi, bus, train via New York

    1. Take the taxi from Destin to Whataburger - Defuniak Springstaxi taxi
    2. Take the bus from Whataburger - Defuniak Springs to Circle K - Gainesville, FLbus bus
    3. Take the bus from Gainesville to Orlando Bus Stationbus bus
    4. Take the train from Orlando to Ny Moynihan Train Hall At Penn Stationtrain train
    5. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    40h 34m
    $416–1,076

  5. Drive 1,150.7 mi

    1. Drive from Destin to Buffalocar car 1,150.7 mi
    19h 39m
    $210–304

  6. Taxi to Northwest Florida Beaches International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Buffalo Niagara International Airport (BUF)plane plane ECP - BUF
    6h 31m
    $340–1,429

  7. Taxi to Pensacola International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)plane plane PNS - BUF
    7h 2m
    $382–1,532

  8. Fly Destin–Fort Walton Beach Airport to Toronto Pearson International Airport, shuttle

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Toronto Pearson International Airport (YYZ)plane plane VPS - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    8h 43m
    $207–620

  9. Drive to Dothan Regional Airport, fly to Buffalo Niagara International Airport

    1. Drive from Destin to Dothan Regional Airport (DHN)car car
    2. Fly from Dothan Regional Airport (DHN) to Buffalo Niagara International Airport (BUF)plane plane DHN - BUF
    7h 54m
    $225–1,210

  10. Taxi, bus via Atlanta

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi taxi
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus bus
    3. Take the bus from Mobile to Atlantabus bus
    4. Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus bus
    5. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    32h 7m
    $312–583

  11. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain train
    5. Take the bus from Pittsburgh to Buffalobus bus
    46h 53m

Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) flights

Calendar38Weekly Planes
Duration5h 20mAverage Duration
Ticket$219Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Buffalo, NY, USA?

Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) 5 times a day.

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