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How to get fromDestin to Buffaloby plane, taxi, bus, train, car or shuttle

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There are 11 ways to get from Destin to Buffalo by plane, taxi, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)planeVPS - BUF
    6h 8m
    $297–1,430

  2. Fly Destin–Fort Walton Beach Airport to Rochester, bus

    cheapest
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Rochester (ROC)planeVPS - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus
    8h 7m
    $197–835

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi
    2. Take the bus from Crestview to Tallahasseebus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus
    4. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus
    5. Take the bus from Cleveland, OH to Buffalo, NYbus
    31h 52m
    $284–542

  4. Taxi, bus, train via New York

    1. Take the taxi from Destin to Whataburger - Defuniak Springstaxi
    2. Take the bus from Whataburger - Defuniak Springs to Circle K - Gainesville, FLbus
    3. Take the bus from Gainesville to Orlando Bus Stationbus
    4. Take the train from Orlando to Ny Moynihan Train Hall At Penn Stationtrain
    5. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain
    40h 29m
    $451–1,136

  5. Drive 1,150.7 mi

    1. Drive from Destin to Buffalocar1,150.7 mi
    19h 28m
    $210–304

  6. Taxi to Northwest Florida Beaches International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Buffalo Niagara International Airport (BUF)planeECP - BUF
    7h 8m
    $370–1,529

  7. Taxi to Pensacola International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)planePNS - BUF
    6h 42m
    $412–1,632

  8. Fly Destin–Fort Walton Beach Airport to Toronto Pearson International Airport, shuttle

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Toronto Pearson International Airport (YYZ)planeVPS - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle
    9h 2m
    $207–610

  9. Drive to Dothan Regional Airport, fly to Buffalo Niagara International Airport

    1. Drive from Destin to Dothan Regional Airport (DHN)car
    2. Fly from Dothan Regional Airport (DHN) to Buffalo Niagara International Airport (BUF)planeDHN - BUF
    11h 30m
    $255–1,310

  10. Taxi, bus via Atlanta

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus
    3. Take the bus from Mobile to Atlantabus
    4. Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus
    5. Take the bus from Cleveland, OH to Buffalo, NYbus
    32h 7m
    $317–573

  11. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi
    2. Take the bus from Crestview to Wildwoodbus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus
    4. Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain
    5. Take the bus from Pittsburgh to Buffalobus
    46h 53m

Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) flights

Calendar26Weekly Planes
Duration5h 56mAverage Duration
Ticket$250Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Buffalo, NY, USA?

American Airlines, Delta, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) 4 times a day.

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