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How to get fromDestin to Buffaloby plane, taxi, bus, train, or car

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There are 10 ways to get from Destin to Buffalo by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane plane VPS - BUF
    5h 50m
    $164–703

  2. Fly Destin–Fort Walton Beach Airport to Toronto Pearson International Airport, bus

    cheapest
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Toronto Pearson International Airport (YYZ)plane plane VPS - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    9h 6m
    $138–483

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Montgomery Intermodal Centerbus bus
    4. Take the bus from Montgomery Intermodal Center to Toledo Bus Stopbus bus
    5. Take the bus from Toledo to Clevelandbus bus
    6. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    35h 27m
    $325–537

  4. Taxi, bus, train via New York

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain train
    5. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    40h 58m
    $539–1,105

  5. Drive  1,150.7 mi

    1. Drive from Destin to Buffalocar car 1,150.7 mi
    19h 38m
    $210–304

  6. Taxi to Northwest Florida Beaches International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Buffalo Niagara International Airport (BUF)plane plane ECP - BUF
    6h 26m
    $268–826

  7. Taxi to Pensacola International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)plane plane PNS - BUF
    6h 47m
    $239–755

  8. Fly Destin–Fort Walton Beach Airport to Rochester, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Rochester (ROC)plane plane VPS - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 36m
    $242–991

  9. Drive to Dothan Regional Airport, fly to Buffalo Niagara International Airport

    1. Drive from Destin to Dothan Regional Airport (DHN)car car
    2. Fly from Dothan Regional Airport (DHN) to Buffalo Niagara International Airport (BUF)plane plane DHN - BUF
    9h 16m
    $141–682

  10. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain train
    5. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    46h 41m
    $504–1,085

Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) flights

Calendar46Weekly Planes
Duration5h 23mAverage Duration
Ticket$127Cheapest Price
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Comparing Your Travel Options

Map of how to get from Destin to Buffalo.ExpandLaunch map view
  • Distance: 986.8 mi
  • Duration: 5h 50m

What companies run services between Destin, FL, USA and Buffalo, NY, USA?

Southwest Airlines, Delta, and American Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) every 4 hours.

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