Rome2Rio

How to get fromDestin to Buffaloby plane, taxi, bus, train, car, or shuttle

Find Transport to Buffalo

See all options

There are 9 ways to get from Destin to Buffalo by plane, taxi, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane plane VPS - BUF
    5h 43m
    $268–1,178

  2. Fly Destin–Fort Walton Beach Airport to Rochester, bus

    cheapest
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Rochester (ROC)plane plane VPS - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 45m
    $200–744

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Montgomery Intermodal Centerbus bus
    4. Take the bus from Montgomery Intermodal Center to Toledo Bus Stopbus bus
    5. Take the bus from Toledo to Clevelandbus bus
    6. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    36h 2m
    $314–587

  4. Taxi, bus, train via New York

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain train
    5. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    40h 58m
    $604–1,135

  5. Drive 1,150.7 mi

    1. Drive from Destin to Buffalocar car 1,150.7 mi
    19h 38m
    $210–304

  6. Taxi to Northwest Florida Beaches International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Buffalo Niagara International Airport (BUF)plane plane ECP - BUF
    6h 12m
    $351–1,277

  7. Taxi to Pensacola International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)plane plane PNS - BUF
    6h 23m
    $353–1,280

  8. Fly Destin–Fort Walton Beach Airport to Toronto Pearson International Airport, shuttle

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Toronto Pearson International Airport (YYZ)plane plane VPS - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    8h 5m
    $218–578

  9. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain train
    5. Take the bus from Pittsburgh to Buffalobus bus
    46h 41m
    $554–1,145

Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) flights

Calendar40Weekly Planes
Duration6h 12mAverage Duration
Ticket$229Cheapest Price
See schedules

Questions & Answers

Map of how to get from Destin to Buffalo.ExpandLaunch map view
  • Distance: 986.7 mi
  • Duration: 5h 43m

What companies run services between Destin, FL, USA and Buffalo, NY, USA?

Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) every 4 hours.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound