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How to get fromDestin to BuffaloBy plane, taxi, bus, train, car, or shuttle

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There are 10 ways to get from Destin to Buffalo by plane, taxi, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Buffalo Niagara International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane plane VPS - BUF
    5h 46m
    $248–1,178

  2. Fly Destin–Fort Walton Beach Airport to Rochester, bus

    cheapest
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Rochester (ROC)plane plane VPS - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 34m
    $200–795

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus bus
    5. Take the bus from Cleveland Bus Station to Buffalobus bus
    32h 37m
    $336–577

  4. Taxi, bus, train via Chicago

    1. Take the taxi from Destin to McDonald's - Crestviewtaxi taxi
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus bus
    3. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    5. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    40h 9m
    $613–1,374

  5. Drive 1,150.7 mi

    1. Drive from Destin to Buffalocar car 1,150.7 mi
    19h 37m
    $210–304

  6. Taxi to Northwest Florida Beaches International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Buffalo Niagara International Airport (BUF)plane plane ECP - BUF
    6h 29m
    $331–1,277

  7. Taxi to Pensacola International Airport, fly to Buffalo Niagara International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)plane plane PNS - BUF
    6h 38m
    $353–1,280

  8. Fly Destin–Fort Walton Beach Airport to Toronto Pearson International Airport, shuttle

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Toronto Pearson International Airport (YYZ)plane plane VPS - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    8h 48m
    $218–598

  9. Drive to Dothan Regional Airport, fly to Buffalo Niagara International Airport

    1. Drive from Destin to Dothan Regional Airport (DHN)car car
    2. Fly from Dothan Regional Airport (DHN) to Buffalo Niagara International Airport (BUF)plane plane DHN - BUF
    7h 51m
    $216–1,058

  10. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain train
    5. Take the bus from Pittsburgh to Buffalobus bus
    46h 53m
    $539–1,090

Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) flights

Calendar45Weekly Planes
Duration5h 43mAverage Duration
Ticket$205Cheapest Price
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Questions & Answers

What companies run services between Destin, FL, USA and Buffalo, NY, USA?

Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF) every 4 hours.

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