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How to get fromPoughkeepsie to Buffaloby train (Amtrak), car, train, plane or bus

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There are 7 ways to get from Poughkeepsie to Buffalo by train (Amtrak), car, train, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Poughkeepsie Amtrak Station to Buffalotrain train Empire Service / ...
    7h 22m
    $50–120

  2. Drive 330.4 mi

    1. Drive from Poughkeepsie to Buffalocar car 330.4 mi
    6h 35m
    $61–88

  3. Train to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    6h
    $154–1,011

  4. Train via Buffalo Depew Station

    1. Take the train from Poughkeepsie Amtrak Station to Buffalo Depew Stationtrain train Maple Leaf / ...
    8h 15m
    $58–114

  5. Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    6h 19m
    $146–873

  6. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    6h 51m
    $123–871

  7. Train to Laguardia Airport, fly to Rochester, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    3. Take the bus from Rochester, NY to Buffalo, NYbus bus
    8h 1m
    $294–716

Poughkeepsie to Buffalo by train

Calendar28Weekly Trains
Duration7h 22mAverage Duration
Ticket$50Cheapest Price
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Questions & Answers

What companies run services between Poughkeepsie, NY, USA and Buffalo, NY, USA?

Amtrak operates a train from Poughkeepsie Amtrak Station to Buffalo 3 times a day. Tickets cost $80–190 and the journey takes 7h 22m. VIA Rail also services this route once daily.

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