• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia

There are 10 ways to get from Poughkeepsie to Buffalo by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  6 h 29 min

  1. Take the train from Poughkeepsie Amtrak Station to Buffalo Amtrak Station Maple Leaf / ...

$60 - $160

Cheapest option

Bus  •  10 h 48 min

  1. Take the bus from Poughkeepsie, NY to Binghamton Poughkeepsie-Binghampton
  2. Take the bus from Binghamton, NY - 81 Chenango Street to Buffalo, NY - 181 Ellicott Street Ny / ...

$57 - $104

8 alternative options

Bus via 4220 Genesee St  •  10 h 52 min

  1. Take the bus from Poughkeepsie, NY to Binghamton Poughkeepsie-Binghampton
  2. Take the bus from Binghamton, NY - 81 Chenango Street to Buffalo Airport, NY Ny

$58 - $106

Drive  •  6 h 17 min

  1. Drive from Poughkeepsie to Buffalo 366 miles

$35 - $55

Train to New York JFK, fly to Buffalo  •  5 h 30 min

  1. Take the train from Poughkeepsie Amtrak Station to New York Penn Station
  2. Fly from New York JFK (JFK) to Buffalo (BUF) JFK - BUF

$103 - $423

Train to New York La Guardia, fly to Buffalo  •  5 h 31 min

  1. Take the train from Poughkeepsie Amtrak Station to New York Penn Station
  2. Fly from New York La Guardia (LGA) to Buffalo (BUF) LGA - BUF

$99 - $424

Train to Newark, fly to Buffalo  •  5 h 44 min

  1. Take the train from Poughkeepsie to Grand Central
  2. Fly from Newark (EWR) to Buffalo (BUF) EWR - BUF

$126 - $514

Train, train to Philadelphia, fly to Buffalo  •  6 h 47 min

  1. Take the train from Poughkeepsie Amtrak Station to New York Penn Station
  2. Take the train from New York Penn Station to Philadelphia 30th Street Station
  3. Fly from Philadelphia (PHL) to Buffalo (BUF) PHL - BUF

$261 - $969

Train to New York La Guardia, fly to Rochester, train  •  7 h 49 min

  1. Take the train from Poughkeepsie Amtrak Station to New York Penn Station
  2. Fly from New York La Guardia (LGA) to Rochester (ROC) LGA - ROC
  3. Take the train from Rochester Amtrak Station to Buffalo Amtrak Station

$149 - $518

Train to Newark, fly to Rochester, train  •  8 h 5 min

  1. Take the train from Poughkeepsie to Grand Central
  2. Fly from Newark (EWR) to Rochester (ROC) EWR - ROC
  3. Take the train from Rochester Amtrak Station to Buffalo Amtrak Station

$151 - $548

Questions & Answers

The cheapest way to get from Poughkeepsie to Buffalo is to drive which costs $35 - $55 and takes 6 h 17 min.

More details

The quickest way to get from Poughkeepsie to Buffalo is to train and fly which costs $100 - $430 and takes 5 h 30 min.

More details

No, there is no direct bus from Poughkeepsie to Buffalo. However, there are services departing from Poughkeepsie, NY and arriving at Buffalo, NY - 181 Ellicott Street via Binghamton, NY - 81 Chenango Street. The journey, including transfers, takes approximately 10 h 48 min.

More details

Yes, there is a direct train departing from Poughkeepsie Amtrak Station station and arriving at Buffalo Amtrak Station station. Services depart four times a day, and operate every day. The journey takes approximately 6 h 29 min.

More details

The distance between Poughkeepsie and Buffalo is 268 miles. The road distance is 366 miles.

Get driving directions

The best way to get from Poughkeepsie to Buffalo without a car is to train which takes 6 h 29 min and costs $60 - $160.

More details

The train from Poughkeepsie Amtrak Station to Buffalo Amtrak Station takes 6 h 29 min including transfers and departs four times a day.

More details

Poughkeepsie to Buffalo bus services, operated by Coach USA, depart from Poughkeepsie, NY station.

More details

Poughkeepsie to Buffalo train services, operated by Amtrak, arrive at Poughkeepsie Amtrak Station.

More details

The best way to get from Poughkeepsie to Buffalo is to train which takes 6 h 29 min and costs $60 - $160. Alternatively, you can bus, which costs $55 - $110 and takes 10 h 48 min.

Mode details

Map of how to get from Poughkeepsie to Buffalo.
Launch map view
  • Distance: 267.8 miles
  • Duration: 6 h 29 min

What companies run services between Poughkeepsie, NY, USA and Buffalo, NY, USA?

Amtrak operates a train from Poughkeepsie to Buffalo 3 times a day. Tickets cost $60 - $160 and the journey takes 6 h 29 min. VIA Rail also services this route once daily. Alternatively, you can take a bus from Poughkeepsie to Buffalo via Binghamton and Binghamton, NY - 81 Chenango Street in around 10 h 48 min.

Airlines
United Airlines
Website
united.com
Flights from New York La Guardia to Buffalo via Washington Dulles
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$220 - $1,600
Flights from Newark to Buffalo
Ave. Duration
1 h 27 min
When
Every day
Estimated price
$120 - $850
Flights from Newark to Buffalo via Washington Dulles
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$120 - $850
Flights from Newark to Rochester
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$120 - $600
Delta
Website
delta.com
Flights from New York JFK to Buffalo
Ave. Duration
1 h 37 min
When
Every day
Estimated price
$90 - $650
Flights from New York La Guardia to Buffalo
Ave. Duration
1 h 34 min
When
Every day
Estimated price
$100 - $700
Flights from New York La Guardia to Buffalo via Boston
Ave. Duration
3 h 57 min
When
Monday to Friday
Estimated price
$100 - $700
Flights from New York La Guardia to Rochester
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$90 - $600
American Airlines
Website
aa.com
Flights from New York La Guardia to Buffalo via Philadelphia
Ave. Duration
3 h 37 min
When
Every day
Estimated price
$130 - $800
Flights from New York La Guardia to Buffalo via Reagan Washington
Ave. Duration
4 h
When
Sunday
Estimated price
$130 - $800
Flights from Philadelphia to Buffalo
Ave. Duration
1 h 24 min
When
Every day
Estimated price
$200 - $1,100
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Buffalo
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$100 - $650
Flights from New York JFK to Buffalo via Boston
Ave. Duration
3 h 38 min
When
Monday to Friday
Estimated price
$100 - $650
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Poughkeepsie Amtrak Station to Buffalo Amtrak Station
Ave. Duration
6 h 29 min
Frequency
3 times a day
Estimated price
$60 - $160
Website
amtrak.com
Coach Seat
$60 - $90
Flexi Coach Seat
$100 - $160
Business Coach Seat
$110 - $160
Room
$270 - $370
Train from Poughkeepsie Amtrak Station to New York Penn Station
Ave. Duration
1 h 33 min
Frequency
Every 3 hours
Estimated price
$27 - $50
Website
amtrak.com
Coach Seat
$27 - $50
Business Seat
$65
Train from Rochester Amtrak Station to Buffalo Amtrak Station
Ave. Duration
1 h 17 min
Frequency
3 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Poughkeepsie to Buffalo
Ave. Duration
6 h 39 min
Frequency
Once daily
Estimated price
$80 - $150
Website
viarail.ca
Escape
$55 - $80
Economy
$80 - $120
EconomyPlus
$100 - $150
Business
$140 - $190
Train from Poughkeepsie to New York
Ave. Duration
1 h 35 min
Frequency
Once daily
Estimated price
$27 - $50
Website
viarail.ca
Coach Seat
$27 - $50
Business Seat
$65
Train from Rochester to Buffalo
Ave. Duration
1 h 22 min
Frequency
Once daily
Estimated price
$40 - $85
Website
viarail.ca
Escape
$19 - $40
Economy
$40 - $55
EconomyPlus
$55 - $85
Business
$55 - $80
Metro-North Railroad (MNR)
Phone
+1 877-690-5116
Website
mta.info
Train from Poughkeepsie to Grand Central
Ave. Duration
1 h 52 min
Frequency
Hourly
Estimated price
$17 - $35
Schedules at
mta.info
Off-peak at station
$17 - $19
Off-peak onboard
$23 - $25
Onboard
$25 - $35
At station
$24 - $27
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from New York Penn Station to Philadelphia 30th Street Station
Ave. Duration
1 h 8 min
Frequency
Every 30 minutes
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Bus operators
Coach USA
Phone
201-225-7500
Website
coachusa.com
Bus from Poughkeepsie, NY to Binghamton
Ave. Duration
4 h 33 min
Frequency
Once daily
Estimated price
$30 - $45
Schedules at
coachusa.com
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Binghamton, NY - 81 Chenango Street to Buffalo, NY - 181 Ellicott Street
Ave. Duration
5 h 15 min
Frequency
5 times a day
Estimated price
$24 - $60
Website
Greyhound.ca
Advanced Purchase
$24 - $35
Online Fare
$30 - $50
Standard Fare
$40 - $60
Refundable
$45 - $70
Bus from Binghamton, NY - 81 Chenango Street to Buffalo Airport, NY
Ave. Duration
4 h 35 min
Frequency
Twice daily
Estimated price
$23 - $60
Website
Greyhound.ca
Advanced Purchase
$23 - $35
Online Fare
$29 - $50
Standard Fare
$40 - $60
Refundable
$45 - $65
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Binghamton, Ny to Buffalo, Ny
Ave. Duration
5 h
Frequency
4 times a day
Estimated price
$27 - $70
Website
greyhound.com
Economy
$27 - $45
Flexible
$50 - $70
Trailways New York
Phone
(800) 858-8555
Website
trailwaysny.com
Bus from Binghamton, NY to Buffalo, NY
Ave. Duration
4 h 15 min
Frequency
3 times a day
Estimated price
$40 - $60
Book at
trailwaysny.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from New York JFK Airport to Buffalo Airport is the direct flight which takes 1 h 26 min.

Search flights

Poughkeepsie to Buffalo bus services, operated by Greyhound Canada, arrive at Buffalo, NY - 181 Ellicott Street station.

More details

Poughkeepsie to Buffalo train services, operated by Amtrak, arrive at Buffalo Amtrak Station.

More details

Yes, the driving distance between Poughkeepsie to Buffalo is 366 miles. It takes approximately 6 h 17 min to drive from Poughkeepsie to Buffalo.

Get driving directions

Delta and JetBlue Airways offer flights from New York JFK Airport to Buffalo Airport.

Search flights

Book your Poughkeepsie to Buffalo train tickets online with Rome2rio.

Search and book

There are 140+ hotels available in Buffalo. Prices start at $59 USD per night.

More details