There are 9 ways to get from Poughkeepsie to Buffalo by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  6 h 39 min

  1. Take the train from Poughkeepsie to Buffalo VIA Rail / ...

$55 - $180

8 alternative options

Bus  •  9 h 55 min

  1. Take the bus from Poughkeepsie, NY to Binghamton Poughkeepsie-Binghampton
  2. Take the bus from Binghamton, Ny to Buffalo, Ny 252 / ...

$61 - $114

Drive  •  6 h 17 min

  1. Drive from Poughkeepsie to Buffalo 366 miles

$35 - $55

Train to New York JFK, fly to Buffalo  •  5 h 11 min

  1. Take the train from Poughkeepsie Amtrak to New York Penn Station
  2. Fly from New York JFK (JFK) to Buffalo (BUF) JFK - BUF

$101 - $440

Train to New York La Guardia, fly to Buffalo  •  5 h 12 min

  1. Take the train from Poughkeepsie Amtrak to New York Penn Station
  2. Fly from New York La Guardia (LGA) to Buffalo (BUF) LGA - BUF

$99 - $443

Train to Newark, fly to Buffalo  •  5 h 12 min

  1. Take the train from Poughkeepsie Amtrak to New York Penn Station
  2. Fly from Newark (EWR) to Buffalo (BUF) EWR - BUF

$135 - $551

Train to Albany, fly to Buffalo  •  5 h 27 min

  1. Take the train from Poughkeepsie Amtrak to Albany-Rensselaer Amtrak
  2. Fly from Albany (ALB) to Buffalo (BUF) ALB - BUF

$75 - $443

Train, train to Philadelphia, fly to Buffalo  •  6 h 46 min

  1. Take the train from Poughkeepsie Amtrak to New York Penn Station
  2. Take the train from New York Penn Station to Philadelphia 30th Street Station
  3. Fly from Philadelphia (PHL) to Buffalo (BUF) PHL - BUF

$261 - $988

Train to New York La Guardia, fly to Rochester, train  •  7 h 38 min

  1. Take the train from Poughkeepsie Amtrak to New York Penn Station
  2. Fly from New York La Guardia (LGA) to Rochester (ROC) LGA - ROC
  3. Take the train from Rochester to Buffalo

$148 - $542

Questions & Answers

The cheapest way to get from Poughkeepsie to Buffalo is to drive which costs $35 - $55 and takes 6 h 17 min.

More details

The quickest way to get from Poughkeepsie to Buffalo is to train and fly which costs $100 - $440 and takes 5 h 11 min.

More details

No, there is no direct bus from Poughkeepsie to Buffalo. However, there are services departing from Poughkeepsie, NY and arriving at Buffalo, Ny via Binghamton, Ny. The journey, including transfers, takes approximately 9 h 55 min.

More details

Yes, there is a direct train departing from Poughkeepsie and arriving at Buffalo. Services depart hourly, and operate every day. The journey takes approximately 6 h 39 min.

More details

The distance between Poughkeepsie and Buffalo is 268 miles. The road distance is 366 miles.

Get driving directions

The best way to get from Poughkeepsie to Buffalo without a car is to train which takes 6 h 39 min and costs $55 - $180.

More details

The train from Poughkeepsie to Buffalo takes 6 h 39 min including transfers and departs hourly.

More details

Poughkeepsie to Buffalo bus services, operated by Coach USA, depart from Poughkeepsie, NY station.

More details

Poughkeepsie to Buffalo train services, operated by VIA Rail, depart from Poughkeepsie station.

More details

The best way to get from Poughkeepsie to Buffalo is to train which takes 6 h 39 min and costs $55 - $180. Alternatively, you can bus, which costs $60 - $120 and takes 9 h 55 min.

Mode details

The quickest flight from New York JFK Airport to Buffalo Airport is the direct flight which takes 1 h 16 min.

Search flights

Poughkeepsie to Buffalo bus services, operated by Greyhound USA, arrive at Buffalo, Ny station.

More details

Map of how to get from Poughkeepsie to Buffalo.
Launch map view
  • Distance: 267.8 miles
  • Duration: 6 h 39 min

What companies run services between Poughkeepsie, NY, USA and Buffalo, NY, USA?

VIA Rail operates a train from Poughkeepsie to Buffalo every 3 hours. Tickets cost $55 - $180 and the journey takes 6 h 39 min. Amtrak also services this route 3 times a day. Alternatively, you can take a bus from Poughkeepsie to Buffalo via Binghamton and Binghamton, Ny in around 9 h 55 min.

Airlines
Delta
Website
delta.com
Flights from New York JFK to Buffalo
Ave. Duration
1 h 38 min
When
Every day
Estimated price
$90 - $650
Flights from New York La Guardia to Buffalo
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$100 - $700
Flights from New York La Guardia to Rochester
Ave. Duration
1 h 27 min
When
Every day
Estimated price
$90 - $600
United Airlines
Website
united.com
Flights from New York La Guardia to Buffalo via Washington Dulles
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$220 - $1,600
Flights from Newark to Buffalo
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$120 - $850
Flights from Newark to Buffalo via Washington Dulles
Ave. Duration
3 h 24 min
When
Every day
Estimated price
$120 - $850
Flights from Philadelphia to Buffalo via Washington Dulles
Ave. Duration
3 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $1,600
American Airlines
Website
aa.com
Flights from New York La Guardia to Buffalo via Reagan Washington
Ave. Duration
3 h 36 min
When
Monday to Friday
Estimated price
$130 - $800
Flights from New York La Guardia to Buffalo via Philadelphia
Ave. Duration
3 h 38 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $800
Flights from Philadelphia to Buffalo
Ave. Duration
1 h 27 min
When
Every day
Estimated price
$200 - $1,100
Flights from Philadelphia to Buffalo via Reagan Washington
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$200 - $1,100
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Buffalo
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$100 - $650
OneJet
Website
onejet.com
Flights from Albany to Buffalo
Ave. Duration
1 h
When
Monday to Friday
Estimated price
$45 - $370
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Poughkeepsie to Buffalo
Ave. Duration
6 h 39 min
Frequency
Every 3 hours
Estimated price
$55 - $180
Website
viarail.ca
Escape
$55 - $80
Economy
$90 - $130
Economy Plus
$130 - $180
Business
$130 - $190
Business Plus/Sleeper
$230 - $330
Train from Poughkeepsie to New York
Ave. Duration
1 h 35 min
Frequency
Every 3 hours
Estimated price
$25 - $75
Website
viarail.ca
Escape
$25 - $40
Economy
$30 - $45
Economy Plus
$50 - $75
Business
$45 - $65
Business Plus/Sleeper
$85 - $120
Train from Poughkeepsie to Albany
Ave. Duration
1 h 15 min
Frequency
Every 3 hours
Estimated price
$25 - $75
Website
viarail.ca
Escape
$25 - $35
Economy
$30 - $45
Economy Plus
$50 - $75
Business
$45 - $65
Business Plus/Sleeper
$80 - $120
Train from Rochester to Buffalo
Ave. Duration
1 h 22 min
Frequency
Every 3 hours
Estimated price
$25 - $75
Website
viarail.ca
Escape
$25 - $35
Economy
$30 - $45
Economy Plus
$50 - $75
Business
$45 - $65
Business Plus/Sleeper
$80 - $120
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Poughkeepsie Amtrak to Buffalo Exchange Street Amtrak
Ave. Duration
6 h 29 min
Frequency
3 times a day
Estimated price
$60 - $160
Website
amtrak.com
Coach Seat
$60 - $90
Flexi Coach Seat
$100 - $160
Business Coach Seat
$110 - $160
Room
$270 - $370
Train from Poughkeepsie Amtrak to New York Penn Station
Ave. Duration
1 h 30 min
Frequency
Every 3 hours
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Train from Poughkeepsie Amtrak to Albany-Rensselaer Amtrak
Ave. Duration
1 h 5 min
Frequency
Every 2 hours
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Train from Rochester Amtrak to Buffalo Exchange Street Amtrak
Ave. Duration
1 h 17 min
Frequency
3 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New York Penn Station to Philadelphia 30th Street Station
Ave. Duration
1 h 7 min
Frequency
Hourly
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Binghamton, Ny to Buffalo, Ny
Ave. Duration
5 h 5 min
Frequency
Every 30 minutes
Estimated price
$28 - $70
Website
greyhound.com
Economy
$28 - $45
Flexible
$50 - $70

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.