Rome2Rio

How to get fromPoughkeepsie to Buffaloby train (Amtrak), train, bus, car or plane

Find Transport to Buffalo

See all options

There are 9 ways to get from Poughkeepsie to Buffalo by train (Amtrak), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Poughkeepsie Amtrak Station to Buffalotrain train Empire Service / ...
    7h 22m
    $50–110

  2. Train, bus

    1. Take the train from Poughkeepsie Amtrak Station to Albany-Rensselaer Amtrak Stationtrain train Empire Service / ...
    2. Take the bus from Albany Bus Terminal, NY to Buffalobus bus Greyhound US0171
    9h
    $70–183

  3. Drive 330.4 mi

    1. Drive from Poughkeepsie to Buffalocar car 330.4 mi
    6h 34m
    $61–88

  4. Train to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    5h 52m
    $144–911

  5. Train via Buffalo Depew Station

    1. Take the train from Poughkeepsie Amtrak Station to Buffalo Depew Stationtrain train Maple Leaf / ...
    8h 16m
    $57–113

  6. Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    6h 8m
    $136–773

  7. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    6h 41m
    $128–832

  8. Train to Laguardia Airport, fly to Rochester, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 6m
    $326–829

  9. Train to Newark Liberty International Airport, fly to Rochester, bus

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane plane EWR - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 55m
    $290–750

Poughkeepsie to Buffalo by train

Calendar28Weekly Trains
Duration7h 22mAverage Duration
Ticket$50Cheapest Price
See schedules

Questions & Answers

What companies run services between Poughkeepsie, NY, USA and Buffalo, NY, USA?

Amtrak operates a train from Poughkeepsie Amtrak Station to Buffalo 3 times a day. Tickets cost $100–230 and the journey takes 7h 22m. VIA Rail also services this route once daily.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Where to next?

Trips from Poughkeepsie

Trips to Buffalo

Popular routes