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How to get fromPoughkeepsie to Buffaloby train (Amtrak), train, bus, car, or plane

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There are 8 ways to get from Poughkeepsie to Buffalo by train (Amtrak), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Poughkeepsie Amtrak Station to Buffalotrain train Empire Service / ...
    7h 12m
    $95–260

  2. Drive 330.4 mi

    cheapest
    1. Drive from Poughkeepsie to Buffalocar car 330.4 mi
    6h 35m
    $61–88

  3. Train, bus

    1. Take the train from Poughkeepsie Amtrak Station to Albany-Rensselaer Amtrak Stationtrain train Empire Service / ...
    2. Take the bus from Albany Bus Terminal, NY to Buffalobus bus Greyhound US0171
    9h 3m
    $65–241

  4. Train to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    5h 37m
    $111–662

  5. Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    5h 50m
    $109–544

  6. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    5h 34m
    $116–584

  7. Train to Laguardia Airport, fly to Rochester, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 16m
    $127–626

  8. Train to Newark Liberty International Airport, fly to Rochester, bus

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane plane EWR - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 5m
    $492–1,418

Poughkeepsie to Buffalo by train

Calendar28Weekly Trains
Duration7h 12mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Poughkeepsie to Buffalo.ExpandLaunch map view
  • Distance: 365.5 mi
  • Duration: 7h 12m

What companies run services between Poughkeepsie, NY, USA and Buffalo, NY, USA?

Amtrak operates a train from Poughkeepsie Amtrak Station to Buffalo 3 times a day. Tickets cost $120–240 and the journey takes 7h 12m. VIA Rail also services this route once daily.

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