The average train between Strasbourg and Mainz takes 3h 25m and the fastest train takes 3h 19m. The train service runs several times per day from Strasbourg to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Strasbourg and Mainz. The earliest departure is at 9:08 AM in the morning, and the last departure from Strasbourg is at 5:13 PM which arrives into Mainz at 8:32 PM. All services require a transfer at Mannheim Hbf and take an average of 3h 25m. The schedules shown below are for the next available departures.

3h 24m • 1 change

3h 23m • 1 change

3h 37m • 1 change

3h 19m • 1 change

3h 24m • 1 change

3h 23m • 1 change

3h 37m • 1 change

3h 19m • 1 change

3h 24m • 1 change

3h 23m • 1 change

3h 37m • 1 change

3h 19m • 1 change

3h 24m • 1 change

3h 23m • 1 change

3h 37m • 1 change

3h 19m • 1 change
Want to know about travelling from Strasbourg to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Strasbourg to Mainz. However, there are services departing from Strasbourg station and arriving at Mainz station via Mannheim Hbf. The journey, including transfers, takes approximately 3h 25m.
Strasbourg to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), depart from Strasbourg station.
Strasbourg to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mainz, Römisches Theater station.
Book your Strasbourg to Mainz train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and TGV inOui.
The distance between Strasbourg and Mainz is 160.4 km. The road distance is 207 km.
You can take a train from Strasbourg to Mainz, Römisches Theater via Mannheim Hbf and Mannheim, Hauptbahnhof in around 2h 43m.