The average train between Strasbourg and Mainz takes 3h 20m and the fastest train takes 2h 9m. The train service runs several times per day from Strasbourg to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Strasbourg and Mainz. The earliest departure is at 9:08 AM in the morning, and the last departure from Strasbourg is at 8:59 PM which arrives into Mainz at 5:38 AM. All services require a transfer, and take on average 3h 20m. The schedules shown below are for the next available departures.

3h 38m • 1 change

3h 27m • 1 change

3h 43m • 1 change

3h 37m • 1 change

3h 28m • 1 change

2h 9m • 1 change

3h 23m • 1 change

3h 23m • 1 change

3h 28m • 1 change

2h 9m • 1 change

3h 23m • 1 change

3h 23m • 1 change

3h 28m • 1 change

2h 9m • 1 change

3h 23m • 1 change

3h 23m • 1 change
Want to know about travelling from Strasbourg to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Strasbourg to Mainz. However, there are services departing from Strasbourg station and arriving at Mainz station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 3h 20m.
Strasbourg to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), depart from Strasbourg Bahnhof station.
Strasbourg to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mainz, Hauptbahnhof station.
Book your Strasbourg to Mainz train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and TGV inOui.
The distance between Strasbourg and Mainz is 160.4 km. The road distance is 212 km.
You can take a train from Strasbourg Bahnhof to Mainz, Hauptbahnhof via Mannheim, Hauptbahnhof in around 1h 57m.