The average train between Strasbourg and Mainz takes 2h 16m and the fastest train takes 2h 5m. The train service runs several times per day from Strasbourg to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Strasbourg and Mainz. The earliest departure is at 9:08 AM in the morning, and the last departure from Strasbourg is at 9:35 PM which arrives into Mainz at 1:22 AM. All services require a transfer at Mannheim Hbf and take an average of 2h 16m. The schedules shown below are for the next available departures.

2h 10m • 1 change

2h 9m • 1 change

2h 48m • 1 change

2h 5m • 1 change

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2h 20m • 1 change

2h 5m • 1 change

2h 10m • 1 change

2h 9m • 1 change

2h 20m • 1 change

2h 5m • 1 change

2h 10m • 1 change

2h 9m • 1 change

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2h 5m • 1 change
Want to know about travelling from Strasbourg to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Strasbourg to Mainz. However, there are services departing from Strasbourg station and arriving at Mainz station via Mannheim Hbf. The journey, including transfers, takes approximately 2h 16m.
Strasbourg to Mainz train services, operated by TGV inOui, depart from Strasbourg station.
Strasbourg to Mainz train services, operated by TGV inOui, arrive at Mainz, Hauptbahnhof station.
Book your Strasbourg to Mainz train tickets online with TGV inOui, Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Strasbourg and Mainz is 160.4 km. The road distance is 208 km.
You can take a train from Strasbourg to Mainz, Hauptbahnhof via Mannheim Hbf and Mannheim, Hauptbahnhof in around 2h 1m.