The average train between Isernia and Ancona takes 9h and the fastest train takes 6h 48m. The train service runs several times per day from Isernia to Ancona. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Isernia and Ancona. The earliest departure is at 6:40 AM in the morning, and the last departure from Isernia is at 8:35 PM which arrives into Ancona at 11:25 AM. All services require a transfer, and take on average 9h. The schedules shown below are for the next available departures.

6h 48m • 1 change

9h 2m • 1 change

7h 22m • 1 change
Arrives next day

7h 4m • 1 change

6h 48m • 1 change

9h 2m • 1 change

7h 22m • 1 change
Arrives next day

7h 4m • 1 change

9h 2m • 1 change

7h 26m • 1 change
Arrives next day

7h 37m • 1 change
Arrives next day

14h 50m • 1 change

6h 48m • 1 change

9h 2m • 1 change

7h 22m • 1 change
Arrives next day

7h 4m • 1 change

9h 2m • 1 change

7h 26m • 1 change
Arrives next day

7h 37m • 1 change
Arrives next day

14h 50m • 1 change

6h 48m • 1 change

9h 2m • 1 change

7h 22m • 1 change
Arrives next day

7h 4m • 1 change
Want to know about travelling from Isernia to Ancona? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Ancona. However, there are services departing from Isernia station and arriving at Ancona station via Roma Termini. The journey, including transfers, takes approximately 9h.
Isernia to Ancona train services, operated by Trenitalia, depart from Isernia station.
Isernia to Ancona train services, operated by Trenitalia, arrive at Ancona station.
Book your Isernia to Ancona train tickets online with Trenitalia and Trenitalia Intercity.
The distance between Isernia and Ancona is 230.1 km. The road distance is 463 km.
You can take a train from Isernia to Ancona via Roma Termini in around 7h 8m.