The average bus between St. Louis and Philadelphia takes 22h 26m and the fastest bus takes 22h 5m. The bus service runs several times per day from St. Louis to Philadelphia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between St. Louis and Philadelphia. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 1:55 PM which arrives into Philadelphia at 1:00 PM. All services run direct with no transfers required, and take on average 22h 26m. The schedules shown below are for the next available departures.
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Want to know about travelling from St. Louis to Philadelphia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from St. Louis station and arriving at Philadelphia station. Services depart 3 times a day, and operate Once daily. The journey takes approximately 22h 26m.
St. Louis to Philadelphia bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Philadelphia bus services, operated by Greyhound USA, arrive at Philadelphia station.
Book your St. Louis to Philadelphia bus tickets online with Greyhound USA.
The distance between St. Louis and Philadelphia is 1,300.6 km. The road distance is 1,467 km.
Greyhound USA operates a bus from St Louis Bus Station to Philadelphia 3 times a day. Tickets cost $150–300 and the journey takes 22h 5m.
