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How to get fromSt. Louis to Philadelphiaby plane, bus (Greyhound), train (Amtrak), car or train

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There are 8 ways to get from St. Louis to Philadelphia by plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Philadelphia International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)planeSTL - PHL
    4h 21m
    $192–492

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from St Louis Bus Station to PhiladelphiabusGreyhound US0421
    22h 5m
    $120–290

  3. Train via Washington (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain
    2. Take the train from Chicago Union Station to Rockville Amtraktrain
    3. Take the train from Washington Union Station to 30th Street Stationtrain
    25h 24m
    $192–1,240

  4. Drive 879.8 mi

    1. Drive from St. Louis to Philadelphiacar879.8 mi
    14h 48m
    $161–232

  5. Fly to Baltimore-Washington International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Baltimore-Washington International Airport (BWI)planeSTL - BWI
    2. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain
    5h 37m
    $226–1,074

  6. Fly to Laguardia Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)planeSTL - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain
    6h 18m
    $228–1,048

  7. Fly to Ronald Reagan Washington National Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Ronald Reagan Washington National Airport (DCA)planeSTL - DCA
    2. Take the train from Washington Union Station to 30th Street Stationtrain
    6h 6m
    $234–1,760

  8. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union StationtrainLincoln Service / ...
    2. Take the train from Chicago Union Station to 30th Street StationtrainCardinal
    31h 51m
    $182–764

St. Louis to Philadelphia by bus (Greyhound)

Calendar21Weekly Buses
Duration22h 5mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Philadelphia, PA, USA?

American Airlines, Southwest Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL) every 4 hours. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Philadelphia 3 times a day. Tickets cost $120–290 and the journey takes 22h 5m.

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