Rome2Rio

How to get fromSt. Louis to Philadelphiaby plane, bus (Greyhound), train (Amtrak), car or train

Find Transport to Philadelphia

See all options

There are 8 ways to get from St. Louis to Philadelphia by plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Philadelphia International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)plane plane STL - PHL
    4h 26m
    $212–492

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from St Louis Bus Station to Philadelphiabus bus Greyhound US0421
    22h 5m
    $85–270

  3. Train via Washington (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Rockville Amtraktrain train
    3. Take the train from Washington Union Station to 30th Street Stationtrain train
    25h 24m
    $171–1,188

  4. Drive 879.8 mi

    1. Drive from St. Louis to Philadelphiacar car 879.8 mi
    14h 57m
    $161–232

  5. Fly to Baltimore-Washington International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Baltimore-Washington International Airport (BWI)plane plane STL - BWI
    2. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain train
    5h 37m
    $226–1,114

  6. Fly to Laguardia Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)plane plane STL - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    6h 22m
    $218–1,058

  7. Fly to Ronald Reagan Washington National Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Ronald Reagan Washington National Airport (DCA)plane plane STL - DCA
    2. Take the train from Washington Union Station to 30th Street Stationtrain train
    6h 6m
    $254–1,960

  8. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to 30th Street Stationtrain train Cardinal
    31h 51m
    $151–662

St. Louis to Philadelphia by bus (Greyhound)

Calendar21Weekly Buses
Duration22h 5mAverage Duration
Ticket$85Cheapest Price
See schedules

Questions & Answers

What companies run services between St. Louis, MO, USA and Philadelphia, PA, USA?

American Airlines, Southwest Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL) every 4 hours. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Philadelphia 3 times a day. Tickets cost $85–270 and the journey takes 22h 5m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Where to next?

Trips from St. Louis

Trips to Philadelphia

Popular routes