The bus between St. Louis and Buffalo takes 27h 45m. The bus runs, on average, 6 times per week from St. Louis to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between St. Louis and Buffalo. The earliest departure is at 5:55 PM in the evening, and the last departure from St. Louis is at 5:55 PM which arrives into Buffalo at 10:40 PM. All services require a transfer at Indianapolis Union Station and take an average of 27h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Buffalo. However, there are services departing from St. Louis station and arriving at Buffalo station via Indianapolis Union Station station. The journey, including transfers, takes approximately 27h 45m.
St. Louis to Buffalo bus services, operated by Greyhound-us, depart from St Louis Bus Station.
St. Louis to Buffalo bus services, operated by Greyhound-us, arrive at Buffalo, NY station.
Book your St. Louis to Buffalo bus tickets online with Greyhound-us and Barons Bus.
The distance between St. Louis and Buffalo is 1,063.3 km. The road distance is 1,306 km.
You can take a bus from St Louis Bus Station to Buffalo, NY via Indianapolis Union Station, Cincinnati Bus Station, and Cincinnati, OH in around 17h 40m.
