Rome2Rio

St. Louis to Detroit Bus Station buses

Find Transport to Detroit Bus Station

View schedule

Trip Overview

The bus between St. Louis and Detroit Bus Station takes 13h 50m. There is at least one bus per day from St. Louis to Detroit Bus Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

13h 50m
Duration
521 mi
Distance
$113
Average price
Once daily
Frequency

St. Louis to Detroit Bus Station bus times

Buses run once daily between St. Louis and Detroit Bus Station. The service departs St. Louis at 2:00 AM at night, which arrives into Detroit Bus Station at 16:50:00. All services require a transfer, and take on average 13h 50m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    Greyhound USAGreyhound USA13h 50m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Greyhound USAGreyhound USA13h 50m • 1 change

Departing Friday, November 6, 2026

  •  → 

    Greyhound USAGreyhound USA13h 50m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Greyhound USAGreyhound USA13h 50m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    Greyhound USAGreyhound USA13h 50m • 1 change

Departing Monday, November 9, 2026

  •  → 

    Greyhound USAGreyhound USA13h 50m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Greyhound USAGreyhound USA13h 50m • 1 change

Frequently asked questions

Want to know about travelling from St. Louis to Detroit Bus Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Detroit Bus Station.ExpandLaunch map view
  • Distance: 521.2 mi
  • Duration: 13h 50m

What companies run services between St. Louis, MO, USA and Detroit Bus Station, MI, USA?

You can take a bus from St Louis Bus Station to Detroit Bus Station via Indianapolis Union Station in around 11h 30m.

Operators