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St. Louis to Ithaca buses

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Trip Overview

The bus between St. Louis and Ithaca takes 44h 15m. The bus runs, on average, 5 times per week from St. Louis to Ithaca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

44h 15m
Duration
1,038 mi
Distance
$298
Average price
5 times a week
Frequency

St. Louis to Ithaca bus times

Buses run 5 times a week between St. Louis and Ithaca. The earliest departure is at 2:05 PM in the afternoon, and the last departure from St. Louis is at 2:05 PM which arrives into Ithaca at 11:20 AM. All services require a transfer at Harrisburg, Pa and take an average of 44h 15m. The schedules shown below are for the next available departures.

Departing Tuesday, October 20, 2026

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    Arrives +2 days

    Greyhound USATrailwaysTrailways44h 15m • 2 changes

Departing Wednesday, October 21, 2026

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    Arrives +2 days

    Greyhound USATrailwaysTrailways44h 15m • 2 changes

Departing Thursday, October 22, 2026

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    Arrives +2 days

    Greyhound USATrailwaysTrailways44h 15m • 2 changes

Departing Friday, October 23, 2026

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    Arrives +2 days

    Greyhound USATrailwaysTrailways44h 15m • 2 changes

Departing Saturday, October 24, 2026

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    Arrives +2 days

    Greyhound USATrailwaysTrailways44h 15m • 2 changes

Frequently asked questions

Want to know about travelling from St. Louis to Ithaca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Ithaca.ExpandLaunch map view
  • Distance: 1,037.9 mi
  • Duration: 44h 15m

What companies run services between St. Louis, MO, USA and Ithaca, NY, USA?

You can take a bus from St Louis Bus Station to Ithaca via Harrisburg, Pa and Scranton, Pa in around 27h 35m.

Operators