Rome2Rio

St. Louis to Ithaca buses

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Trip Overview

The bus between St. Louis and Ithaca takes 44h 15m. The bus runs, on average, 5 times per week from St. Louis to Ithaca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

44h 15m
Duration
1,036 mi
Distance
$302
Average price
5 times a week
Frequency

St. Louis to Ithaca bus times

Buses run 5 times a week between St. Louis and Ithaca. The service departs St. Louis at 2:05 PM in the afternoon, which arrives into Ithaca at 11:20:00. All services require a transfer at Harrisburg, Pa and take an average of 44h 15m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives +2 days

    Greyhound USATrailwaysTrailways44h 15m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives +2 days

    Greyhound USATrailwaysTrailways44h 15m • 2 changes

Departing Friday, November 13, 2026

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    Arrives +2 days

    Greyhound USATrailwaysTrailways44h 15m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives +2 days

    Greyhound USATrailwaysTrailways44h 15m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives +2 days

    Greyhound USATrailwaysTrailways44h 15m • 2 changes

Frequently asked questions

Want to know about travelling from St. Louis to Ithaca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Ithaca.ExpandLaunch map view
  • Distance: 1,035.6 mi
  • Duration: 44h 15m

What companies run services between St. Louis, MO, USA and Ithaca, NY, USA?

You can take a bus from St Louis Bus Station to Ithaca via Harrisburg, Pa and Scranton, Pa in around 27h 35m.

Operators