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How to get fromSt. Louis to Ithacaby plane, train, bus, bus (Greyhound) or car

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There are 9 ways to get from St. Louis to Ithaca by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ithaca Tompkins Regional Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Ithaca Tompkins Regional Airport (ITH)planeSTL - ITH
    7h 12m
    $112–602

  2. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain
    2. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain
    3. Take the bus from Syracuse Bus Station to Ithacabus
    20h 57m
    $150–376

  3. Bus

    1. Take the bus from St Louis Bus Station to Harrisburg Bus Stationbus
    2. Take the bus from Harrisburg, PA to Scranton, PAbus
    3. Take the bus from Scranton, Pa to Ithacabus246
    27h 5m
    $129–276

  4. Drive 862.3 mi

    1. Drive from St. Louis to Ithacacar862.3 mi
    15h 5m
    $158–228

  5. Fly to Syracuse Hancock International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Syracuse Hancock International Airport (SYR)planeSTL - SYR
    2. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    8h 16m
    $192–1,008

  6. Fly to Rochester, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Rochester (ROC)planeSTL - ROC
    2. Take the bus from Rochester, NY to Ithaca, NYbus
    8h 53m
    $152–812

  7. Fly to Greater Binghamton Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Greater Binghamton Airport (BGM)planeSTL - BGM
    2. Take the bus from Binghamton to Ithacabus
    8h 35m
    $150–682

  8. Fly to Elmira/Corning Regional Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Elmira/Corning Regional Airport (ELM)planeSTL - ELM
    2. Take the bus from Transit Center - PO Side to Tompkins County Librarybus
    8h 47m

  9. Fly to Laguardia Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)planeSTL - LGA
    2. Take the bus from New York, NY to Ithaca, NYbus
    9h 51m
    $196–536

St. Louis to Ithaca by train and bus

Calendar10Weekly Services
Duration20h 57mAverage Duration
Ticket$150Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Ithaca, NY, USA?

United Airlines and Delta fly from Lambert–St. Louis International Airport (STL) to Ithaca Tompkins Regional Airport (ITH) 4 times a day. Alternatively, you can take a bus from St Louis Bus Station to Ithaca via Harrisburg Bus Station, Harrisburg, PA, and Scranton, Pa in around 27h 5m.

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