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St. Louis to Niagara Falls buses

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Trip Overview

The average bus between St. Louis and Niagara Falls takes 21h 34m and the fastest bus takes 21h 33m. There is at least one bus per day from St. Louis to Niagara Falls. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 34m
Duration
806 mi
Distance
$155
Average price
Once daily
Frequency

St. Louis to Niagara Falls bus times

Buses run once daily between St. Louis and Niagara Falls. The service departs St. Louis at 2:00 AM at night, which arrives into Niagara Falls at 00:34:35. All services require a transfer at Columbus and take an average of 21h 34m. The schedules shown below are for the next available departures.

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USABarons BusNFTA21h 34m • 2 changes

Departing Tuesday, November 17, 2026

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    Arrives next day

    Greyhound USABarons BusNFTA21h 34m • 2 changes

Departing Wednesday, November 18, 2026

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    Arrives next day

    Greyhound USABarons BusNFTA21h 34m • 2 changes

Departing Thursday, November 19, 2026

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    Arrives next day

    Greyhound USABarons BusNFTA21h 34m • 2 changes

Departing Friday, November 20, 2026

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    Arrives next day

    Greyhound USABarons BusNFTA21h 34m • 2 changes

Departing Saturday, November 21, 2026

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    Arrives next day

    Greyhound USABarons BusNFTA21h 35m • 2 changes

Frequently asked questions

Want to know about travelling from St. Louis to Niagara Falls? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Niagara Falls.ExpandLaunch map view
  • Distance: 805.6 mi
  • Duration: 21h 34m

What companies run services between St. Louis, MO, USA and Niagara Falls, NY, USA?

You can take a bus from St Louis Bus Station to Main Street & Pine Avenue via Columbus and Ellicott Street & MTC Static in around 20h 33m.

Operators