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St. Louis to DeSoto buses

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Trip Overview

The bus between St. Louis and DeSoto takes 29h 58m. The bus runs, on average, 3 times per week from St. Louis to DeSoto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

29h 58m
Duration
724 mi
Distance
$150
Average price
3 times a week
Frequency

St. Louis to DeSoto bus times

Buses run 3 times a week between St. Louis and DeSoto. The service departs St. Louis at 8:40 AM in the morning, which arrives into DeSoto at 14:38:00. All services require a transfer at Oklahoma City Bus Station and take an average of 29h 58m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USADallas Area Rapid Transit (DART)Dallas Area Rapid Transit (DART)29h 58m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USADallas Area Rapid Transit (DART)Dallas Area Rapid Transit (DART)29h 58m • 3 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USADallas Area Rapid Transit (DART)Dallas Area Rapid Transit (DART)29h 58m • 3 changes

Frequently asked questions

Want to know about travelling from St. Louis to DeSoto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to DeSoto.ExpandLaunch map view
  • Distance: 723.7 mi
  • Duration: 29h 58m

What companies run services between St. Louis, MO, USA and DeSoto, TX, USA?

You can take a bus from St Louis Bus Station to Glenn Heights P & R via Oklahoma City Bus Station, Downtown Dallas / Deep Ellum, Gaston @ Good Latimer - S- Ns, Houston @ Young - S - Mb, and Wood @ Record - W - Fs in around 16h 2m.

Operators