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St. Louis to Pittsburgh buses

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Trip Overview

The average bus between St. Louis and Pittsburgh takes 14h 3m and the fastest bus takes 12h 55m. The bus service runs several times per day from St. Louis to Pittsburgh. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 3m
Duration
606 mi
Distance
$120
Average price
3 times a day
Frequency

St. Louis to Pittsburgh bus times

Buses run 3 times a day between St. Louis and Pittsburgh. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 1:55 PM which arrives into Pittsburgh at 3:50 AM. All services run direct with no transfers required, and take on average 14h 3m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from St. Louis to Pittsburgh? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Pittsburgh.ExpandLaunch map view
  • Distance: 606.4 mi
  • Duration: 14h 3m

What companies run services between St. Louis, MO, USA and Pittsburgh, PA, USA?

Greyhound USA operates a bus from St Louis Bus Station to Pittsburgh Intermodal Station 3 times a day. Tickets cost $100–200 and the journey takes 12h 55m.

Operators