The average bus between St. Louis and Cape Cod takes 37h 27m and the fastest bus takes 33h 3m. The bus service runs several times per day from St. Louis to Cape Cod. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between St. Louis and Cape Cod. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Cape Cod at 8:48 AM. All services require a transfer at Port Authority Bus Terminal and take an average of 37h 27m. The schedules shown below are for the next available departures.
Arrives next day



36h 48m • 3 changesArrives +2 days



42h 43m • 3 changesArrives next day



36h 48m • 3 changesArrives next day



34h 3m • 3 changesArrives +2 days



42h 43m • 3 changesWant to know about travelling from St. Louis to Cape Cod? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Cape Cod. However, there are services departing from St. Louis station and arriving at Cape Cod station via Port Authority Bus Terminal. The journey, including transfers, takes approximately 37h 27m.
St. Louis to Cape Cod bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Cape Cod bus services, operated by Greyhound USA, arrive at Hyannis Transportation Center station.
The distance between St. Louis and Cape Cod is 1,729 km. The road distance is 2,161 km.
You can take a bus from St Louis Bus Station to Town Hall Lawton Bus Shelter via Port Authority Bus Terminal, New York, Boston, Boston South Buses, and Hyannis Transportation Center in around 33h 47m.