The average bus between St. Louis and Cape Cod takes 39h 34m and the fastest bus takes 34h 48m. There is at least one bus per day from St. Louis to Cape Cod. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between St. Louis and Cape Cod. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 8:45 AM which arrives into Cape Cod at 8:48 AM. All services require a transfer at Port Authority Bus Terminal and take an average of 39h 34m. The schedules shown below are for the next available departures.
Arrives next day



35h 48m • 3 changes
Arrives +2 days



46h 3m • 3 changes
Arrives next day



35h 48m • 3 changes
Arrives +2 days



46h 3m • 3 changes
Want to know about travelling from St. Louis to Cape Cod? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Cape Cod. However, there are services departing from St. Louis station and arriving at Cape Cod station via Port Authority Bus Terminal. The journey, including transfers, takes approximately 39h 34m.
St. Louis to Cape Cod bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Cape Cod bus services, operated by Greyhound USA, arrive at Hyannis Transportation Center station.
The distance between St. Louis and Cape Cod is 1,729 km. The road distance is 2,115 km.
You can take a bus from St Louis Bus Station to Town Hall Lawton Bus Shelter via Port Authority Bus Terminal, Providence Bus Terminal, and Hyannis Transportation Center in around 33h 53m.