The average bus between Portland and Cape Cod takes 5h 42m and the fastest bus takes 4h 33m. The bus service runs several times per day from Portland to Cape Cod. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Portland and Cape Cod. The earliest departure is at 3:15 AM at night, and the last departure from Portland is at 8:00 PM which arrives into Cape Cod at 6:48 AM. All services require a transfer at Boston, MA - South Station and take an average of 5h 42m. The schedules shown below are for the next available departures.


5h 33m • 2 changes


5h 33m • 2 changes


4h 33m • 2 changes


5h 18m • 2 changes


5h 33m • 2 changes


5h 33m • 2 changes


4h 33m • 2 changes


5h 18m • 2 changes


5h 33m • 2 changes


5h 33m • 2 changes


4h 33m • 2 changes


5h 18m • 2 changes


5h 33m • 2 changes


5h 33m • 2 changes


4h 33m • 2 changes


5h 18m • 2 changes
Want to know about travelling from Portland to Cape Cod? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portland to Cape Cod. However, there are services departing from Portland station and arriving at Cape Cod station via Boston, MA - South Station station. The journey, including transfers, takes approximately 5h 42m.
Portland to Cape Cod bus services, operated by Amtrak Thruway, depart from Portland, ME station.
Portland to Cape Cod bus services, operated by Amtrak Thruway, arrive at Hyannis Transportation Center station.
The distance between Portland and Cape Cod is 219.9 km. The road distance is 298 km.
You can take a bus from Portland, ME to Town Hall Lawton Bus Shelter via Boston, MA - South Station, Boston South Buses, and Hyannis Transportation Center in around 5h 45m.