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Roanoke to Buffalo buses

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Trip Overview

The average bus between Roanoke and Buffalo takes 24h 40m and the fastest bus takes 24h 35m. There is at least one bus per day from Roanoke to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 40m
Duration
857 mi
Distance
$181
Average price
Once daily
Frequency

Roanoke to Buffalo bus times

Buses run once daily between Roanoke and Buffalo. The service departs Roanoke at 4:25 AM at night, which arrives into Buffalo at 05:00:00. All services require a transfer at Washington Union Station and take an average of 24h 40m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA24h 35m • 2 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA25h 10m • 2 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA24h 35m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA24h 35m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA24h 35m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA24h 35m • 2 changes

Frequently asked questions

Want to know about travelling from Roanoke to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Roanoke to Buffalo.ExpandLaunch map view
  • Distance: 857.1 mi
  • Duration: 24h 40m

What companies run services between Roanoke, VA, USA and Buffalo, NY, USA?

You can take a bus from Roanoke Bus Stop to Buffalo via Washington Union Station and Newark Penn Station in around 19h 50m.

Operators