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Sicily to Isernia buses

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Trip Overview

The bus between Sicily and Isernia takes 18h 9m. The bus runs, on average, 6 times per week from Sicily to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

18h 9m
Duration
839 km
Distance
€45
Average price
6 times a week
Frequency

Sicily to Isernia bus times

Buses run 6 times a week between Sicily and Isernia. The service departs Sicily at 5:35 PM in the evening, which arrives into Isernia at 11:44:00. All services require a transfer at Stazione Centrale Pensilina Esterna and take an average of 18h 9m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

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    Arrives next day

    AMAT Palermo S.p.A.Autoservizi Salemi SrlFlixBus18h 9m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    AMAT Palermo S.p.A.Autoservizi Salemi SrlFlixBus18h 9m • 2 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    AMAT Palermo S.p.A.Autoservizi Salemi SrlFlixBus18h 9m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    AMAT Palermo S.p.A.Autoservizi Salemi SrlFlixBus18h 9m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    AMAT Palermo S.p.A.Autoservizi Salemi SrlFlixBus18h 9m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    AMAT Palermo S.p.A.Autoservizi Salemi SrlFlixBus18h 9m • 2 changes

Frequently asked questions

Want to know about travelling from Sicily to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Sicily to Isernia.ExpandLaunch map view
  • Distance: 839.1 km
  • Duration: 18h 9m

What companies run services between Sicily, Italy and Isernia, Italy?

You can take a bus from Piazza Boiardo to Isernia via Stazione Centrale Pensilina Esterna, Palermo Terminal Bus, Caserta pzza Garibaldi, and Caserta Terminal Bus in around 13h 24m.

Operators