The average bus between Palestrina and Isernia takes 4h 7m and the fastest bus takes 3h 29m. The bus service runs several times per day from Palestrina to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Palestrina and Isernia. The earliest departure is at 8:58 AM in the morning, and the last departure from Palestrina is at 4:43 PM which arrives into Isernia at 8:40 PM. All services require a transfer at Ponte Mammolo and take an average of 4h 7m. The schedules shown below are for the next available departures.


4h 27m • 2 changes


4h 8m • 2 changes


4h 3m • 2 changes


3h 57m • 2 changes


4h 27m • 2 changes


4h 8m • 2 changes


4h 3m • 2 changes


3h 57m • 2 changes


4h 27m • 2 changes


4h 8m • 2 changes


4h 3m • 2 changes


3h 57m • 2 changes


4h 27m • 2 changes


4h 8m • 2 changes


4h 3m • 2 changes


3h 57m • 2 changes
Want to know about travelling from Palestrina to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Palestrina to Isernia. However, there are services departing from Palestrina station and arriving at Isernia station via ROMA | Ponte Mammolo. The journey, including transfers, takes approximately 4h 7m.
Palestrina to Isernia bus services, operated by Cotral S.p.A., depart from PALESTRINA | Ist. Luzzatti-Livatino # f12259 station.
Palestrina to Isernia bus services, operated by Cotral S.p.A., arrive at Isernia station.
The distance between Palestrina and Isernia is 115.3 km. The road distance is 220 km.
You can take a bus from PALESTRINA | Ist. Luzzatti-Livatino # f12259 to Isernia via Ponte Mammolo and Roma, Autostazione Tiburtina in around 4h 26m.