There are 4 ways to get from Palestrina to Isernia by train (Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Valmontone to Frosinonetrain Re
- Take the train from Frosinone to Iserniatrain Re
3h 41m€17–25Bus
cheapest- Take the bus from PALESTRINA | Ist. Luzzatti-Livatino # f12259 to ROMA | Ponte Mammolobus Gz33a / ...
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
4h 25m€12–35Drive 142.4 km
- Drive from Palestrina to Iserniacar 142.4 km
1h 40m€26–38Bus, train
- Take the bus from SAN CESAREO | Via Casilina piazza G.Cesare # f6044 to COLLEFERRO | Stazione FS # f4937bus
- Take the train from Colleferro-Segni-Pal to Frosinonetrain Re
- Take the train from Frosinone to Iserniatrain Re
4h 50m€17–27
Palestrina to Isernia by bus and train (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Palestrina to Isernia is to bus and train which costs €17 - €28 and takes 4h 50m.
The fastest way to get from Palestrina to Isernia is to drive which takes 1h 40m and costs €25 - €40.
No, there is no direct bus from Palestrina to Isernia. However, there are services departing from PALESTRINA | Ist. Luzzatti-Livatino # f12259 and arriving at Isernia via Ponte Mammolo and Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 25m.
No, there is no direct train from Palestrina to Isernia. However, there are services departing from Valmontone and arriving at Isernia via Frosinone. The journey, including transfers, takes approximately 3h 41m.
The distance between Palestrina and Isernia is 155 km. The road distance is 142.4 km.
The best way to get from Palestrina to Isernia without a car is to train which takes 3h 41m and costs €17 - €26.
It takes approximately 3h 41m to get from Palestrina to Isernia, including transfers.
Palestrina to Isernia bus services, operated by Cotral S.p.A., depart from PALESTRINA | Ist. Luzzatti-Livatino # f12259 station.
Palestrina to Isernia train services, operated by Trenitalia, depart from Valmontone station.
The best way to get from Palestrina to Isernia is to train which takes 3h 41m and costs €17 - €26. Alternatively, you can bus, which costs €11 - €40 and takes 4h 25m.
What companies run services between Palestrina, Lazio, Italy and Isernia, Italy?
You can take a bus from PALESTRINA | A.Moro # f15104 to Isernia via VALMONTONE | stazione FS # f3602, Valmontone, and Frosinone in around 3h 41m. Alternatively, you can take a bus from PALESTRINA | Ist. Luzzatti-Livatino # f12259 to Isernia via Ponte Mammolo and Roma, Autostazione Tiburtina in around 4h 25m.
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Valmontone to Frosinone
- Ave. Duration
- 47 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–7
- Website
- Trenitalia
Train from Frosinone to Isernia
- Ave. Duration
- 1h 18m
- Frequency
- Twice daily
- Estimated price
- €12–17
- Website
- Trenitalia
Train from Colleferro-Segni-Pal to Frosinone
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Website
- Trenitalia
Train from Frosinone to Isernia
- Ave. Duration
- 1h 18m
- Frequency
- Twice daily
- Estimated price
- €12–17
- Website
- Trenitalia
- Phone
- 800 174 471
- Website
- Cotral S.p.A.
Bus from PALESTRINA | Ist. Luzzatti-Livatino # f12259 to ROMA | Ponte Mammolo
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- €2–4
- Schedules at
- Cotral S.p.A.
Bus from SAN CESAREO | Via Casilina piazza G.Cesare # f6044 to COLLEFERRO | Stazione FS # f4937
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- €1–3
- Schedules at
- Cotral S.p.A.
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €15–23
- Website
- Flixbus
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Booking & Getting There
Palestrina to Isernia bus services, operated by Cotral S.p.A., arrive at ROMA | Ponte Mammolo station.
Palestrina to Isernia train services, operated by Trenitalia, arrive at Frosinone station.
Yes, the driving distance between Palestrina to Isernia is 142 km. It takes approximately 1h 40m to drive from Palestrina to Isernia.
There are 454+ hotels available in Isernia.