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How to get fromPalestrina to Iserniaby train (Trenitalia), bus, or car

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There are 3 ways to get from Palestrina to Isernia by train (Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Zagarolo to Cassinotrain train Re
    2. Take the train from Cassino to Iserniatrain train Re
    3h 21m
    €30–46
  2. Bus

    cheapest
    1. Take the bus from PALESTRINA | Ist. Luzzatti-Livatino # f12259 to ROMA | Ponte Mammolobus bus Gz23a / ...
    2. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus Rome Tiburtina
    4h 34m
    €12–37
  3. Drive 142.4 km

    1. Drive from Palestrina to Iserniacar car 142.4 km
    1h 40m
    €23–32

Palestrina to Isernia by bus

Calendar27Weekly Buses
Duration4h 34mAverage Duration
Ticket€12Cheapest Price
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Questions & Answers

What companies run services between Palestrina, Italy and Isernia, Italy?

You can take a vehicle from Palestrina to Isernia via Zagarolo and Cassino in around 3h 21m. Alternatively, you can take a bus from PALESTRINA | Ist. Luzzatti-Livatino # f12259 to Isernia via Ponte Mammolo and Roma, Autostazione Tiburtina in around 4h 34m.

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