The bus between Palermo and Siena takes 22h 40m. There is at least one bus per day from Palermo to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Palermo and Siena. The earliest departure is at 6:00 PM in the evening, and the last departure from Palermo is at 6:00 PM which arrives into Siena at 4:40 PM. All services require a transfer, and take on average 22h 40m. The schedules shown below are for the next available departures.
Want to know about travelling from Palermo to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Palermo to Siena. However, there are services departing from Palermo station and arriving at Siena station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 22h 40m.
Palermo to Siena bus services, operated by Autoservizi Salemi Srl, depart from Palermo Terminal Bus station.
Palermo to Siena bus services, operated by Autoservizi Salemi Srl, arrive at Siena - p.zza Rosselli station.
Book your Palermo to Siena bus tickets online with Autoservizi Salemi Srl and Autolinee Federico.
The distance between Palermo and Siena is 600.9 km. The road distance is 1,175 km.
You can take a bus from Palermo Terminal Bus to Siena - p.zza Rosselli via Roma, Autostazione Tiburtina in around 16h 15m.