Rome2Rio

Palermo to Madrid buses

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Trip Overview

The bus between Palermo and Madrid takes 2d 19h. The bus runs, on average, 5 times per week from Palermo to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 19h
Duration
3,236 km
Distance
€356
Average price
5 times a week
Frequency

Palermo to Madrid bus times

Buses run 5 times a week between Palermo and Madrid. The service departs Palermo at 3:25 PM in the afternoon, which arrives into Madrid at 09:30:00. All services require a transfer, and take on average 2d 19h. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives +3 days

    FlixBusFlixBus2d 19h • 1 change

Departing Monday, November 16, 2026

  •  → 

    Arrives +3 days

    FlixBusFlixBus2d 19h • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Arrives +3 days

    FlixBusFlixBus2d 19h • 1 change

Departing Wednesday, November 18, 2026

  •  → 

    Arrives +3 days

    FlixBusFlixBus2d 19h • 1 change

Departing Thursday, November 19, 2026

  •  → 

    Arrives +3 days

    FlixBusFlixBus2d 19h • 1 change

Frequently asked questions

Want to know about travelling from Palermo to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Palermo to Madrid.ExpandLaunch map view
  • Distance: 3,236.3 km
  • Duration: 2d 19h

What companies run services between Palermo, Italy and Madrid, Spain?

You can take a bus from Palermo to Madrid via Milan in around 46h 25m.

Operators