The average bus between Vasto and Siena takes 7h 24m and the fastest bus takes 6h 40m. The bus service runs several times per day from Vasto to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Vasto and Siena. The earliest departure is at 2:20 AM at night, and the last departure from Vasto is at 5:10 PM which arrives into Siena at 12:40 AM. All services require a transfer, and take on average 7h 24m. The schedules shown below are for the next available departures.

6h 55m • 1 change

6h 55m • 1 change

8h 10m • 1 change

6h 40m • 1 change

6h 55m • 1 change

6h 55m • 1 change

8h 10m • 1 change

6h 40m • 1 change

6h 55m • 1 change

6h 55m • 1 change

8h 10m • 1 change

6h 40m • 1 change

6h 55m • 1 change

6h 55m • 1 change

8h 10m • 1 change

6h 40m • 1 change

6h 55m • 1 change

6h 55m • 1 change

8h 10m • 1 change

6h 40m • 1 change

6h 55m • 1 change

8h 50m • 1 change

6h 40m • 1 change

7h 49m • 1 change
Want to know about travelling from Vasto to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Vasto to Siena. However, there are services departing from Vasto station and arriving at Siena station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 7h 24m.
Vasto to Siena bus services, operated by Dicarlo Bus, depart from Vasto station.
Vasto to Siena bus services, operated by Dicarlo Bus, arrive at Siena station.
Book your Vasto to Siena bus tickets online with Dicarlo Bus and FlixBus.
The distance between Vasto and Siena is 306.7 km. The road distance is 504 km.
You can take a bus from Vasto to Siena via Roma, Autostazione Tiburtina in around 7h 9m.