There are 9 ways to get from Palermo to Siena by plane, train, train (Trenitalia), bus, ferry, car ferry, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane PMO - FLR
- Take the train from Firenze S.M.N. to Sienatrain
5h 52m€58–177Fly to Perugia Sant'Egidio Airport, bus
cheapest- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)plane PMO - PEG
- Take the bus from Perugia to Sienabus
7h 8m€42–291Train (Trenitalia)
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
15h 45m€108–278Bus
- Take the bus from Palermo to Sienabus N597
16h 30m€75–130Ferry, train, bus
- Take the ferry from Port of Palermo to Port of Civitavecchiaferry
- Take the train from Civitavecchia to Grossetotrain Re
- Take the bus from Grosseto F.S. to Siena-Via Tozzibus 51G
17h 28mFly to Pisa International Airport, train
- Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane PMO - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
5h 39m€58–225Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Palermo Airport (PMO) to Bologna Guglielmo Marconi Airport (BLQ)plane PMO - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
6h 50m€52–265Train via Chiusi (Trenitalia)
- Take the train from Palermo Centrale to Roma Terminitrain Ic
- Take the train from Roma Termini to Chiusi-Chianciano T.train
- Take the train from Chiusi-Chianciano T. to Sienatrain Re
18h 2m€103–249Car ferry, drive
- Take the car ferry from Port of Palermo to Livornocarferry
- Drive from Livorno to Sienacar
21h 15m€59–83
Palermo to Siena by train (Trenitalia)
Questions & Answers
The cheapest way to get from Palermo to Siena is to car ferry and drive which costs €55 - €85 and takes 21h 15m.
The fastest way to get from Palermo to Siena is to fly and train which takes 5h 39m and costs €55 - €230.
Yes, there is a direct bus departing from Palermo and arriving at Siena. Services depart once daily, and operate every day. The journey takes approximately 16h 30m.
No, there is no direct train from Palermo to Siena. However, there are services departing from Palermo Centrale and arriving at Siena via Roma Termini and Firenze S.M.N.. The journey, including transfers, takes approximately 15h 45m.
The distance between Palermo and Siena is 773 km.
The best way to get from Palermo to Siena without a car is to train which takes 15h 45m and costs €100 - €280.
It takes approximately 5h 52m to get from Palermo to Siena, including transfers.
Palermo to Siena bus services, operated by FlixBus, depart from Palermo station.
Palermo to Siena train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Palermo to Siena is to train which takes 15h 45m and costs €100 - €280. Alternatively, you can bus, which costs €75 - €130 and takes 16h 30m.
What companies run services between Palermo, Italy and Siena, Italy?
You can take a train from Palermo Centrale to Siena via Roma Termini and Firenze S.M.N. in around 15h 45m. Alternatively, FlixBus operates a bus from Palermo to Siena once daily. Tickets cost €75–130 and the journey takes 16h 30m.
- Website
- ryanair.com
Flights from Palermo Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–190
Flights from Palermo Airport to Pisa International Airport via Bari
- Ave. Duration
- 3h 35m
- When
- Saturday
- Estimated price
- €35–190
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €35–190
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €30–240
- Website
- ita-airways.com
Flights from Palermo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €70–150
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- €45–150
- Website
- volotea.com
Flights from Palermo Airport to Florence Peretola Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €30–130
- Website
- flyulendo.com
Flights from Palermo Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €20–150
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a day
- Estimated price
- €15–23
- Website
- https://www.trenitalia.com/en.html
Train from Civitavecchia to Grosseto
- Ave. Duration
- 1h 11m
- Frequency
- Every 2 hours
- Estimated price
- €7–11
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €5–8
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
Train from Chiusi-Chianciano T. to Siena
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 34m
- Frequency
- Once daily
- Estimated price
- €85–200
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- €25–60
- Website
- https://www.trenitalia.com/en.html
Train from Civitavecchia to Grosseto
- Ave. Duration
- 50 min
- Frequency
- 3 times a day
- Estimated price
- €10–24
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 48m
- Frequency
- 3 times a day
- Estimated price
- €14–35
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
Train from Civitavecchia to Grosseto
- Ave. Duration
- 44 min
- Frequency
- 5 times a day
- Estimated price
- €15–30
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €28–40
- Website
- https://www.italotreno.it/en
- Smart Economy
- €28–40
- Smart Flex
- €29–40
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once a week
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Palermo to Siena
- Ave. Duration
- 16h 30m
- Frequency
- Once daily
- Estimated price
- €75–130
- Website
- https://www.flixbus.co.uk
Bus from Perugia to Siena
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €6–12
- Website
- https://www.flixbus.co.uk
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Grosseto F.S. to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Website
- https://www.at-bus.it/en
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Ferry from Port of Palermo to Port of Civitavecchia
- Ave. Duration
- 12h
- Frequency
- Once a week
- Estimated price
- €55–99
- Website
- https://www.gnv.it/en
- Seat
- €55–65
- Cabin
- €93–99
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Car ferry from Port of Palermo to Livorno
- Ave. Duration
- 19h 30m
- Frequency
- 3 times a week
- Estimated price
- €40–60
- Website
- https://www.grimaldi-lines.com/en/
Want to know more about travelling around Italy
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More Questions & Answers
Palermo to Siena bus services, operated by FlixBus, arrive at Siena station.
Palermo to Siena train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Palermo to Siena train tickets online with Omio.
Book your Palermo to Siena bus tickets online with Omio and FlixBus.
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