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How to get fromPalermo to Sienaby plane, train, ferry, car, train (Trenitalia) or bus

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There are 9 ways to get from Palermo to Siena by plane, train, ferry, car, train (Trenitalia), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)plane plane PMO - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    5h 52m
    €67–208
  2. Bus

    cheapest
    1. Take the bus from Palermo to Sienabus bus N597
    16h 30m
    €40–120
  3. Ferry, drive

    1. Take the ferry from Port of Palermo to Port of Naplesferry ferry
    2. Drive from Port of Naples to Sienacar car
    12h 36m
    €106–152
  4. Train

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Florence Santa Maria Novellatrain train
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    15h 58m
    €61–173
  5. Fly to Pisa International Airport, train

    1. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane plane PMO - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    5h 39m
    €84–235
  6. Fly to Perugia Sant'Egidio Airport, bus

    1. Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)plane plane PMO - PEG
    2. Take the bus from Perugia to Sienabus bus
    5h 38m
    €80–376
  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Palermo Airport (PMO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane PMO - BLQ
    2. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 54m
    €80–270
  8. Bus via Rome

    1. Take the bus from Palermo Terminal Bus to Roma, Autostazione Tiburtinabus bus Itabus
    2. Take the bus from Roma, Autostazione Tiburtina to Siena - p.zza Rossellibus bus Lamezia Terme
    17h 25m
    €45–53
  9. Train via Chiusi (Trenitalia)

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Chiusi-Chianciano T.train train
    3. Take the train from Chiusi-Chianciano T. to Sienatrain train Re
    18h
    €47–142

Palermo to Siena by train

Calendar7Weekly Trains
Duration15h 58mAverage Duration
Ticket€61Cheapest Price
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Questions & Answers

What companies run services between Palermo, Italy and Siena, Italy?

You can take a train from Palermo Centrale to Siena via Roma Termini and Firenze S.M.N. in around 15h 58m. Alternatively, FlixBus operates a bus from Palermo to Siena once daily. Tickets cost €40–120 and the journey takes 16h 30m.

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