The average bus between Siena and Rome takes 3h 30m and the fastest bus takes 2h 45m. The bus service runs several times per day from Siena to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Siena and Rome. The earliest departure is at 11:15 AM in the morning, and the last departure from Siena is at 4:25 PM which arrives into Rome at 7:10 PM. All services run direct with no transfers required, and take on average 3h 30m. The schedules shown below are for the next available departures.
Want to know about travelling from Siena to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Siena station and arriving at Rome station. Services depart twice daily, and operate 3 times a day. The journey takes approximately 3h 30m.
Siena to Rome bus services, operated by Autolinee Federico, depart from Siena station.
Siena to Rome bus services, operated by Autolinee Federico, arrive at Roma station.
Book your Siena to Rome bus tickets online with Autolinee Federico and FlixBus.
The distance between Siena and Rome is 184.4 km. The road distance is 230 km.
Itabus S.p.A. operates a bus from Siena to Roma hourly. Tickets cost €13–24 and the journey takes 2h 50m. Two other operators also service this route.