Rome2Rio

Siena to Rome buses

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Trip Overview

The average bus between Siena and Rome takes 2h 42m and the fastest bus takes 2h 40m. The bus service runs several times per day from Siena to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 42m
Duration
226 km
Distance
€22
Average price
Twice daily
Frequency

Siena to Rome bus times

Buses run twice daily between Siena and Rome. The earliest departure is at 7:10 AM in the morning, and the last departure from Siena is at 10:55 AM which arrives into Rome at 1:35 PM. All services run direct with no transfers required, and take on average 2h 42m. The schedules shown below are for the next available departures.

Departing Thursday, October 15, 2026

  •  → 

    bus bus 2h 40m • Direct

Departing Friday, October 16, 2026

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    bus bus 2h 45m • Direct
  •  → 

    bus bus 2h 40m • Direct

Departing Saturday, October 17, 2026

  •  → 

    bus bus 2h 45m • Direct
  •  → 

    bus bus 2h 40m • Direct

Departing Sunday, October 18, 2026

  •  → 

    bus bus 2h 45m • Direct
  •  → 

    bus bus 2h 40m • Direct

Departing Monday, October 19, 2026

  •  → 

    bus bus 2h 45m • Direct
  •  → 

    bus bus 2h 40m • Direct

Departing Tuesday, October 20, 2026

  •  → 

    bus bus 2h 45m • Direct
  •  → 

    bus bus 2h 40m • Direct

Departing Wednesday, October 21, 2026

  •  → 

    bus bus 2h 45m • Direct
  •  → 

    bus bus 2h 40m • Direct

Frequently asked questions

Want to know about travelling from Siena to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Siena to Rome.ExpandLaunch map view
  • Distance: 226 km
  • Duration: 2h 42m

What companies run services between Siena, Italy and Rome, Italy?

FlixBus operates a bus from Siena to Roma, Autostazione Tiburtina twice daily. Tickets cost €18–28 and the journey takes 2h 40m.

Operators