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Myrtle Beach to Buffalo buses

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Trip Overview

The bus between Myrtle Beach and Buffalo takes 27h 50m. The bus runs, on average, 3 times per week from Myrtle Beach to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

27h 50m
Duration
1,096 mi
Distance
$218
Average price
3 times a week
Frequency

Myrtle Beach to Buffalo bus times

Buses run 3 times a week between Myrtle Beach and Buffalo. The service departs Myrtle Beach at 1:10 PM in the afternoon, which arrives into Buffalo at 17:00:00. All services require a transfer at Fayetteville Bus Station and take an average of 27h 50m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA27h 50m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA27h 50m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA27h 50m • 2 changes

Frequently asked questions

Want to know about travelling from Myrtle Beach to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Myrtle Beach to Buffalo.ExpandLaunch map view
  • Distance: 1,096.3 mi
  • Duration: 27h 50m

What companies run services between Myrtle Beach, SC, USA and Buffalo, NY, USA?

You can take a bus from Myrtle Beach Bus Station to Buffalo via Fayetteville Bus Station and Newark Penn Station in around 23h 10m.

Operators