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Myrtle Beach to Orlando buses

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Trip Overview

The bus between Myrtle Beach and Orlando takes 44h 50m. The bus runs, on average, 5 times per week from Myrtle Beach to Orlando. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

44h 50m
Duration
591 mi
Distance
$122
Average price
5 times a week
Frequency

Myrtle Beach to Orlando bus times

Buses run 5 times a week between Myrtle Beach and Orlando. The service departs Myrtle Beach at 12:40 PM in the afternoon, which arrives into Orlando at 09:30:00. All services require a transfer at Camden and take an average of 44h 50m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA44h 50m • 2 changes

Departing Monday, November 16, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA44h 50m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA44h 50m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA44h 50m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA44h 50m • 2 changes

Frequently asked questions

Want to know about travelling from Myrtle Beach to Orlando? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Myrtle Beach to Orlando.ExpandLaunch map view
  • Distance: 590.8 mi
  • Duration: 44h 50m

What companies run services between Myrtle Beach, SC, USA and Orlando, FL, USA?

You can take a bus from Myrtle Beach Bus Station to Orlando Bus Station via Camden and Jacksonville in around 15h 10m.

Operators