Rome2Rio

Myrtle Beach to Guelph buses

Find Transport to Guelph

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The bus between Myrtle Beach and Guelph takes 44h 30m. The bus runs, on average, 2 times per week from Myrtle Beach to Guelph. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

44h 30m
Duration
1,961 km
Distance
$596
Average price
Twice a week
Frequency

Myrtle Beach to Guelph bus times

Buses run twice a week between Myrtle Beach and Guelph. The service departs Myrtle Beach at 1:10 PM in the afternoon, which arrives into Guelph at 09:40:00. All services require a transfer at Fayetteville Bus Station and take an average of 44h 30m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USATrailwaysGO Transit44h 30m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USATrailwaysGO Transit44h 30m • 3 changes

Frequently asked questions

Want to know about travelling from Myrtle Beach to Guelph? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Myrtle Beach to Guelph.ExpandLaunch map view
  • Distance: 1,961.1 km
  • Duration: 44h 30m

What companies run services between Myrtle Beach, SC, USA and Guelph, ON, Canada?

You can take a bus from Myrtle Beach Bus Station to Guelph Central GO Bus via Fayetteville Bus Station, Newark, Mississauga, and Winston Churchill Transitway Station in around 27h 9m.

Operators