The average bus between Key West and St. Louis takes 40h 9m and the fastest bus takes 38h 51m. There is at least one bus per day from Key West to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Key West and St. Louis. The earliest departure is at 7:39 AM in the morning, and the last departure from Key West is at 4:15 PM which arrives into St. Louis at 8:20 AM. All services require a transfer at Big Pine Key - Auto Store / NAPA MM30 and take an average of 40h 9m. The schedules shown below are for the next available departures.
Want to know about travelling from Key West to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Key West to St. Louis. However, there are services departing from N Roosevelt & 3rd Street station and arriving at St Louis Bus Station via Big Pine Key - Auto Store / NAPA MM30 station, Miami Airport Station and Atlanta Bus Station. The journey, including transfers, takes approximately 40h 9m.
Key West to St. Louis bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
Key West to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
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The distance between Key West and St. Louis is 1754.1 km. The road distance is 2176 km.
You can take a bus from N Roosevelt & 3rd Street to St Louis Bus Station via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Atlanta Bus Station in around 30h 58m.
