Rome2Rio

Key West to Biloxi buses

Find Transport to Biloxi

View schedule

Trip Overview

The bus between Key West and Biloxi takes 29h 55m. The bus runs, on average, 5 times per week from Key West to Biloxi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

29h 55m
Duration
1,296 mi
Distance
$269
Average price
5 times a week
Frequency

Key West to Biloxi bus times

Buses run 5 times a week between Key West and Biloxi. The service departs Key West at 4:15 PM in the afternoon, which arrives into Biloxi at 21:10:00. All services require a transfer at Big Pine Key - Auto Store / NAPA MM30 and take an average of 29h 55m. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

  •  → 

    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAFlixbus USA29h 55m • 4 changes

Departing Friday, October 23, 2026

  •  → 

    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAFlixbus USA29h 55m • 4 changes

Departing Saturday, October 24, 2026

  •  → 

    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAFlixbus USA29h 55m • 4 changes

Departing Sunday, October 25, 2026

  •  → 

    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAFlixbus USA29h 55m • 4 changes

Departing Monday, October 26, 2026

  •  → 

    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAFlixbus USA29h 55m • 4 changes

Frequently asked questions

Want to know about travelling from Key West to Biloxi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Key West to Biloxi.ExpandLaunch map view
  • Distance: 1,295.6 mi
  • Duration: 29h 55m

What companies run services between Key West, FL, USA and Biloxi, MS, USA?

You can take a bus from N Roosevelt & 3rd Street to Biloxi via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Atlanta Bus Station, Garnett Station, Doraville Station, and Atlanta in around 27h 45m.

Operators