The average bus between Wisconsin and St. Louis takes 10h 34m and the fastest bus takes 9h 10m. The bus service runs several times per day from Wisconsin to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Wisconsin and St. Louis. The earliest departure is at 6:30 AM in the morning, and the last departure from Wisconsin is at 7:55 PM which arrives into St. Louis at 6:25 AM. All services require a transfer, and take on average 10h 34m. The schedules shown below are for the next available departures.

9h 10m • 1 change

14h 20m • 1 change
Arrives next day

10h 30m • 1 change

9h 10m • 1 change

11h 30m • 1 change
Arrives next day

10h 30m • 1 change
Want to know about travelling from Wisconsin to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Wisconsin to St. Louis. However, there are services departing from Wisconsin station and arriving at St. Louis station via Chicago Bus Station station. The journey, including transfers, takes approximately 10h 34m.
Wisconsin to St. Louis bus services, operated by Flixbus USA, depart from Milwaukee Intermodal Station.
Wisconsin to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Book your Wisconsin to St. Louis bus tickets online with Flixbus USA and Greyhound USA.
The distance between Wisconsin and St. Louis is 646.7 km. The road distance is 657 km.
You can take a bus from Milwaukee Intermodal Station to St Louis Bus Station via Chicago Bus Station in around 8h 45m.