Rome2Rio

Key West to Mobile buses

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Trip Overview

The bus between Key West and Mobile takes 27h 34m. The bus runs, on average, 6 times per week from Key West to Mobile. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

27h 34m
Duration
987 mi
Distance
$206
Average price
6 times a week
Frequency

Key West to Mobile bus times

Buses run 6 times a week between Key West and Mobile. The service departs Key West at 4:15 PM in the afternoon, which arrives into Mobile at 18:49:34. All services require a transfer at Big Pine Key - Auto Store / NAPA MM30 and take an average of 27h 34m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAThe WAVE27h 34m • 4 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAThe WAVE27h 34m • 4 changes

Departing Tuesday, November 17, 2026

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    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAThe WAVE27h 34m • 4 changes

Departing Wednesday, November 18, 2026

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    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAThe WAVE27h 34m • 4 changes

Departing Thursday, November 19, 2026

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    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAThe WAVE27h 34m • 4 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    Key West TransitGreyhound USAGreyhound USAGreyhound USAThe WAVE27h 34m • 4 changes

Frequently asked questions

Want to know about travelling from Key West to Mobile? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Key West to Mobile.ExpandLaunch map view
  • Distance: 987.3 mi
  • Duration: 27h 34m

What companies run services between Key West, FL, USA and Mobile, AL, USA?

You can take a bus from N Roosevelt & 3rd Street to Govt EB Mid Block Past Joachim St via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Tallahassee, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 28h 23m.

Operators