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How to get fromKey West to Mobileby plane, shuttle, bus, car, or bus (Greyhound)

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There are 7 ways to get from Key West to Mobile by plane, shuttle, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mobile Regional Airport

    best
    1. Fly from Key West International Airport (EYW) to Mobile Regional Airport (MOB)plane plane EYW - MOB
    4h 56m
    $122–474

  2. Fly to Pensacola International Airport, bus

    cheapest
    1. Fly from Key West International Airport (EYW) to Pensacola International Airport (PNS)plane plane EYW - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    7h 56m
    $71–319

  3. Shuttle, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    24h 5m
    $334–441

  4. Drive  859 mi

    1. Drive from Key West to Mobilecar car 859 mi
    15h 30m
    $157–227

  5. Fly to Destin–Fort Walton Beach Airport, drive

    1. Fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS)plane plane EYW - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    7h 6m
    $91–402

  6. Fly to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT)plane plane EYW - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    6h 45m
    $169–585

  7. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    28h 23m
    $147–244

Key West to Mobile by bus and foot

Calendar7Weekly Services
Duration28h 23mAverage Duration
Ticket$147Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West to Mobile.ExpandLaunch map view
  • Distance: 595.8 mi
  • Duration: 4h 56m

What companies run services between Key West, FL, USA and Mobile, AL, USA?

Delta, American Airlines, and United Airlines fly from Key West International Airport (EYW) to Mobile Regional Airport (MOB) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Govt EB Mid Block Past Joachim St via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Tallahassee, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 28h 23m.

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