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How to get fromKey West to Mobileby plane, bus, train, car, taxi, shuttle or bus (Greyhound, Flixbus)

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There are 10 ways to get from Key West to Mobile by plane, bus, train, car, taxi, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mobile Regional Airport

    best
    1. Fly from Key West International Airport (EYW) to Mobile Regional Airport (MOB)plane plane EYW - MOB
    7h 45m
    $107–504

  2. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Airport Station to Lake Worth Beach Stationtrain train
    4. Take the bus from El Bodegan Grocery 5 - Lake Worth to Love's Travel Stop - Loxleybus bus
    23h 24m
    $205–389

  3. Drive 859 mi

    1. Drive from Key West to Mobilecar car 859 mi
    15h 28m
    $157–227

  4. Fly to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT)plane plane EYW - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    7h 15m
    $184–695

  5. Fly to Destin–Fort Walton Beach Airport, bus

    1. Fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS)plane plane EYW - VPS
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus bus
    7h 29m
    $227–694

  6. Fly to Pensacola International Airport, bus

    1. Fly from Key West International Airport (EYW) to Pensacola International Airport (PNS)plane plane EYW - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    8h 25m
    $207–919

  7. Fly to Northwest Florida Beaches International Airport, taxi, bus

    1. Fly from Key West International Airport (EYW) to Northwest Florida Beaches International Airport (ECP)plane plane EYW - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Whataburger - Defuniak Springstaxi taxi
    3. Take the bus from Whataburger - Defuniak Springs to Love's Travel Stop - Loxleybus bus
    8h 50m
    $307–824

  8. Fly to Tallahassee, bus

    1. Fly from Key West International Airport (EYW) to Tallahassee (TLH)plane plane EYW - TLH
    2. Take the bus from Flying J Travel Cntr - Tallahassee, FL to Love's Travel Stop - Loxleybus bus
    9h 50m
    $257–939

  9. Shuttle, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    24h 45m
    $223–441

  10. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    24h 55m
    $125–284

Key West to Mobile by bus and foot

Calendar13Weekly Services
Duration24h 55mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

What companies run services between Key West, FL, USA and Mobile, AL, USA?

Delta and American Airlines fly from Key West International Airport (EYW) to Mobile Regional Airport (MOB) 4 times a day. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Water NB at St Louis St via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Tallahassee, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 24h 55m.

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