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Key West to Sarasota buses

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Trip Overview

The average bus between Key West and Sarasota takes 22h and the fastest bus takes 21h 19m. The bus service runs several times per day from Key West to Sarasota. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h
Duration
400 mi
Distance
$78
Average price
Twice daily
Frequency

Key West to Sarasota bus times

Buses run twice daily between Key West and Sarasota. The earliest departure is at 7:39 AM in the morning, and the last departure from Key West is at 4:15 PM which arrives into Sarasota at 1:35 PM. All services require a transfer at Big Pine Key - Auto Store / NAPA MM30 and take an average of 22h. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit22h 50m • 3 changes
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    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit21h 20m • 3 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit22h 50m • 3 changes
  •  → 

    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit21h 20m • 3 changes

Departing Tuesday, November 17, 2026

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    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit21h 20m • 3 changes

Departing Wednesday, November 18, 2026

  •  → 

    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit22h 50m • 3 changes
  •  → 

    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit21h 20m • 3 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit22h 50m • 3 changes
  •  → 

    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit21h 20m • 3 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit22h 50m • 3 changes
  •  → 

    Arrives next day

    Key West TransitGreyhound USAFlixbus USASarasota County Area Transit21h 19m • 3 changes

Frequently asked questions

Want to know about travelling from Key West to Sarasota? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Key West to Sarasota.ExpandLaunch map view
  • Distance: 400 mi
  • Duration: 22h

What companies run services between Key West, FL, USA and Sarasota, FL, USA?

You can take a bus from N Roosevelt & 3rd Street to Ringling Blvd @ East Ave via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 12h 21m.

Operators